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关于此项目
经验公式（希尔记法）:
C50H88BF2N5O17P2
化学文摘社编号:
分子量:
1142.01
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
TopFluor™ PI(4)P, Avanti Research™ - A Croda Brand 810185P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 50 μg (with stopper and crimp cap (810185P-50ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 810185P
shipped in
dry ice
storage temp.
−20°C
Application
TopFluor™ PI(4)P has been used as fluorescently labeled phosphoinositide to examine phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) interaction with anionic lipids.
General description
Phosphatidylinositol 4-phosphate (PI4P) is a precursor of phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P2]. It is present in the membranes of Golgi apparatus.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (810185P-50ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Biophysical methods for the characterization of PTEN/lipid bilayer interactions
Harishchandra RK, et al.
Methods, 77, 125-135 (2015)
Xiaojun Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 32(7), 1732-1741 (2016-02-02)
Phosphatidylinositol phosphate (PIP) lipids are critical to many cell signaling pathways, in part by acting as molecular beacons that recruit peripheral membrane proteins to specific locations within the plasma membrane. Understanding the biophysics of PIP-protein interactions is critical to developing
PI4P and PI (4, 5) P2 are essential but independent lipid determinants of membrane identity
Hammond GRV, et al.
Science, 337(6095), 727-730 (2012)
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