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关于此项目
经验公式(希尔记法):
C34H59N6O13P
化学文摘社编号:
分子量:
790.84
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
16:0-06:0 NBD PS, Avanti Research™ - A Croda Brand 810192C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810192C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810192C
concentration
1 mg/mL (810192C-1mg)
shipped in
dry ice
storage temp.
−20°C
Application
16:0-06:0 NBD PS or 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) is suitable to measure the enzyme specificity of lipoteichoic acid (LTA) synthase (LtaS) and in liposomes to determine the role of phospholipid scramblase 1 (PLSCR1) in phospholipid scrambling.
Biochem/physiol Actions
Phosphatidylserine (PS) contributes to the clearance of apoptotic cells. It is involved in maintaining the nerve cell membrane and myelin sheath. It is associated with cognitive disability in Alzheimer′s disease.
General description
Phosphatidylserine (PS) is a minor phospholipid present in the membranes of prokaryotic and eukaryotic cells. It comprises 2-10% of total phospholipids, enriched in brain. NBD PS is labelled at the headgroup of PS with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD).
Packaging
5 mL Amber Glass Screw Cap Vial (810192C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
法规信息
危险化学品
易制毒化学品(2类)
此项目有
Nobuto Arashiki et al.
Biochemistry, 55(25), 3504-3513 (2016-06-09)
An asymmetric distribution of phospholipids in the membrane bilayer is inseparable from physiological functions, including shape preservation and survival of erythrocytes, and by implication other cells. Aminophospholipids, notably phosphatidylserine (PS), are confined to the inner leaflet of the erythrocyte membrane
Maria Mercedes Palomino et al.
Microbiology (Reading, England), 159(Pt 11), 2416-2426 (2013-09-10)
The probiotic Gram-positive bacterium Lactobacillus casei BL23 is naturally confronted with salt-stress habitats. It has been previously reported that growth in high-salt medium, containing 0.8 M NaCl, leads to modifications in the cell envelope of this bacterium. In this study
Jean E Vance et al.
Progress in lipid research, 44(4), 207-234 (2005-06-28)
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and enzymes that are involved in PS biosynthesis in bacteria, yeast, plants and mammalian cells and discuss
Mirka E Wörmann et al.
Molecular microbiology, 79(3), 566-583 (2011-01-25)
Lipoteichoic acid (LTA) is an important cell wall polymer in Gram-positive bacteria. The enzyme responsible for polyglycerolphosphate LTA synthesis is LtaS, first described in Staphylococcus aureus. Four LtaS orthologues, LtaS(BS) , YfnI, YqgS and YvgJ, are present in Bacillus subtilis.
Soumi Mukherjee et al.
Chemistry and physics of lipids, 127(1), 91-101 (2004-01-07)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. NBD-labeled lipids have previously been used to monitor the organization and
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