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Merck
CN

810195C

Avanti

18:1-12:0 NBD PS

Avanti Research - A Croda Brand

别名:

1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt)

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关于此项目

经验公式(希尔记法):
C42H73N6O13P
CAS Number:
分子量:
901.04
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
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Product Name

18:1-12:0 NBD PS, Avanti Research - A Croda Brand 810195C

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mL (810195C-1mg)

制造商/商品名称

Avanti Research - A Croda Brand 810195C

浓度

1 mg/mL (810195C-1mg)

运输

dry ice

储存温度

−20°C

一般描述

Phosphatidylserine (PS) is a minor membrane phospholipid. This anionic phospholipid contains a polar head group and two long hydrophobic acyl chains. 1 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) PS is a fluorescent probe containing NBD at the headgroup of PS.

应用

18:1-12:0 NBD PS or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt) has been used in donor liposomes to determine the phospholipid transfer activity of the synaptic vesicle membrane protein, VAT-1 and phosphatidic acid (PA) transfer by Ups1−Mdm35 system in mitochondria. 18:1-12:0 NBD PS is also suitable for the determination of in vitro phosphatidylserine decarboxylase (Psd1) activity.

包装

5 mL Amber Glass Screw Cap Vial (810195C-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

法规信息

易制毒化学品(2类)
危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Structural and mechanistic insights into phospholipid transfer by Ups1?Mdm35 in mitochondria
Yasunori W, et al.
Nature Communications null
The distribution and function of phosphatidylserine in cellular membranes
Leventis PA and Grinstein S
Annual Review of Biophysics null
Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
Jonathan R, et al.
Developmental Cell null
Jonathan R Friedman et al.
Developmental cell, 44(2), 261-270 (2018-01-02)
Spatial organization of phospholipid synthesis in eukaryotes is critical for cellular homeostasis. The synthesis of phosphatidylcholine (PC), the most abundant cellular phospholipid, occurs redundantly via the ER-localized Kennedy pathway and a pathway that traverses the ER and mitochondria via membrane
Structural Basis for Phosphatidylethanolamine Biosynthesis by Bacterial Phosphatidylserine Decarboxylase
Yasunori W, et al.
Structure null

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