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主要文件

810205X

Avanti

NBD Sphingosine

Avanti Research - A Croda Brand

别名:

D-erythro-Sphingosine-N-NBD

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About This Item

经验公式(希尔记法):
C24H39N5O5
CAS Number:
分子量:
477.60
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25

Product Name

NBD Sphingosine, omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, chloroform:methanol (8:2)

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mL (810205X-250ug)

制造商/商品名称

Avanti Research - A Croda Brand 810205X

浓度

0.25 mg/mL (810205X-250ug)

运输

dry ice

储存温度

−20°C

一般描述

Sphingosine is the most bioactive sphingoid with the common long chain base in sphingolipids. It is a constituent of the cell membrane. 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) sphingosine is a derivative of sphingosine attached with the fluorescent probe, NBD group.

应用

NBD Sphingosine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol may be used:
  • as a negative control to determine the binding of Atg12-Atg5 conjugate with phosphatidylethanolamine (PE)-containing liposomes
  • to label sphingosine kinase 1 (SphK1) in order to determine its role in endocytic membrane trafficking
  • to generate 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD)-ceramide C16

生化/生理作用

Sphingosine serves as a precursor for ceramide. It is involved in the inhibition of protein kinase C in human platelets.

包装

5 mL Amber Glass Screw Cap Vial (810205X-250ug)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

>125.5 °F

闪点(°C)

> 51.95 °C


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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