810209P
Avanti
C6-NBD Ceramide
Avanti Research™ - A Croda Brand
别名:
N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810209P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
运输
dry ice
储存温度
−20°C
SMILES字符串
[N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO
InChI
1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+/t25-,27+/m0/s1
InChI key
HZIRBXILQRLFIK-VPZZKNKNSA-N
一般描述
C6-NBD ceramide is a fluorescent labelled compound, known to be useful for the detection of enzymatic action. C6-NBD ceramide is preferred over radioactive compounds.
应用
C6-NBD Ceramide is suitable as a substrate for sphingomyelin synthase activity assay.
生化/生理作用
Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthases family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.
包装
5 mL Amber Glass Screw Cap Vial (810209P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Handbook of Glycosyltransferases and Related Genes, 5-5 (2011)
A role for ceramides, but not sphingomyelins, as antagonists of insulin signaling and mitochondrial metabolism in C2C12 myotubes
Park M, et al.
The Journal of Biological Chemistry, 291(46), 23978-23988 (2016)
Mammalian ceramide synthases
Levy M and Futerman AH
IUBMB Life, 62(5), 347-356 (2010)
商品
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