产品名称
脱氢麦角甾醇（DHE）, ergosta-5,7,9(11),22-tetraen-3β-ol, powder
SMILES string
O[C@H]1CC[C@]2(C(=CC=C3[C@H]4[C@@]([C@H](CC4)[C@H](C)\C=C\[C@@H](C(C)C)C)(CC=C32)C)C1)C
InChI
1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1
InChI key
QSVJYFLQYMVBDR-CMNOFMQQSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (with stopper and crimp cap (810253P-1mg))
manufacturer/tradename
Avanti Research™ - A Croda Brand 810253P
shipped in
dry ice
storage temp.
−70°C
Application
脱氢麦角固醇（DHE）适用于将DHE从供体（LD）群体转移至受体（LA）脂质体。
Biochem/physiol Actions
脱氢麦角固醇（DHE）用于可视化细胞内运输和细胞内运输动力学。
General description
脱氢麦角固醇（DHE）是一种荧光固醇，具有与胆固醇相似的生物物理特性。它存在于酵母细胞和其他真菌中。
Packaging
2 mL 琥珀色血清小瓶（带有胶塞和钳口盖）(810253P-1 mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Mohsen Pourmousa et al.
The journal of physical chemistry. B, 118(26), 7345-7357 (2014-06-04)
Although dehydroergosterol (DHE) is one of the most commonly used cholesterol (CHOL) reporters, it has remained unclear why it performs well compared with most other CHOL analogues and what its possible limitations are. We present a comprehensive study of the
Molecular basis for sterol transport by StART-like lipid transfer domains
Horenkamp FA, et al.
The Embo Journal, 37(6) (2018)
Reynold Homan et al.
Analytical biochemistry, 441(1), 80-86 (2013-07-16)
We describe a simple but sensitive fluorescence method to accurately detect the esterification activity of lecithin:cholesterol acyltransferase (LCAT). The new assay protocol employs a convenient mix, incubate, and measure scheme. This is possible by using the fluorescent sterol dehydroergosterol (DHE)
Olav Garvik et al.
Chemistry and physics of lipids, 159(2), 114-118 (2009-05-30)
The fluorescent sterol dehydroergosterol (DHE) is often used as a marker for cholesterol in cellular studies. We show by vesicle fluctuation analysis that DHE has a lower ability than cholesterol to stiffen lipid bilayers suggesting less efficient packing with phospholipid
Daniel Wüstner et al.
Microscopy research and technique, 74(1), 92-108 (2010-12-25)
Dehydroergosterol (DHE) is an intrinsically fluorescent sterol with absorption/emission in the ultraviolet (UV) region and biophysical properties similar to those of cholesterol. We compared the potential of UV-sensitive low-light-level wide-field (UV-WF) imaging with that of multiphoton (MP) excitation microscopy to
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