810255P
Avanti
TopFluor™胆固醇
Avanti Research™ - A Croda Brand
别名:
Bodipy胆固醇；Bdp-Chol
描述
23-(dipyrrometheneboron difluoride)-24-norcholesterol
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810255P-1mg)
pkg of 1 × 10 mg (810255P-10mg)
pkg of 1 × 5 mg (810255P-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
运输
dry ice
储存温度
−20°C
一般描述
附着在BODIPY上的生物分子在可见光下很容易被吸收。它导致更大的荧光量子产率。它具有很高的光稳定性，并且对极性和pH的变化不太敏感。
应用
TOPFLUOR™适用于:
- 胆固醇摄取测定
- 在活细胞实验中用于BODIPY胆固醇标记
- 通过聚乙烯醇（PVA）辅助的脂质溶胀形成巨大的Janus脂质体
生化/生理作用
BODIPY标记的胆固醇具有与天然胆固醇相似的特性。它可充当活细胞的胆固醇标志物，并有助于运输细胞内的胆固醇。它也可能有助于指示脂质储存疾病。
包装
5 mL棕色玻璃螺旋盖小瓶（810255P-10mg）
5 mL棕色玻璃螺旋盖小瓶（810255P-1mg）
5 mL棕色玻璃螺旋盖小瓶（810255P-5mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Janus Liposomes: Gel-Assisted Formation and Bioaffinity-Directed Clustering
Wang M, et al.
Langmuir, 34(25), 7509-7518 (2018)
Zaiguo Li et al.
The Journal of organic chemistry, 71(4), 1718-1721 (2006-02-14)
Analogues of cholesterol (compounds 1 and 2) and coprostanol (compound 3) containing the BODIPY fluorophore in the aliphatic tail of the free sterol have been synthesized starting with bisnorcholenic acid, cholenic acid 3beta-acetate, and lithocholic acid, respectively. An ester linkage
Robert M Littleton et al.
BMC complementary and alternative medicine, 12, 105-105 (2012-07-25)
Consumers are increasingly turning to plant-based complementary and alternative medicines to treat hypercholesterolemia. Many of these treatments are untested and their efficacy is unknown. This multitude of potential remedies necessitates a model system amenable to testing large numbers of organisms
Salvatore Chiantia et al.
Biochimica et biophysica acta, 1778(5), 1356-1364 (2008-03-19)
Ceramide-induced alterations in the lateral organization of membrane proteins can be involved in several biological contexts, ranging from apoptosis to viral infections. In order to investigate such alterations in a simple model, we used a combined approach of atomic force
Impaired Cholesterol-Uptake Capacity of HDL Might Promote Target-Lesion Revascularization by Inducing Neoatherosclerosis After Stent Implantation
Nagano Y, et al.
Journal of the American Heart Association, 8(9), e011975-e011975 (2019)
商品
Explore full-spectrum fluorophores, fluorescent lipids, and probes for imaging, membrane studies, and labeling with TopFluor™, squaraines, and more.
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