810283P
Avanti
TopFluor™ PS
Avanti Research™ - A Croda Brand
别名:
1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phospho-L-serine (ammonium salt)
Product Name
TopFluor™ PS, Avanti Research™ - A Croda Brand 810283P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810283P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810283P
运输
dry ice
储存温度
−20°C
一般描述
TopFluor™, a fluorescent molecule carries dipyrromethene boron difluoride moiety. It is linked to several lipid molecules by means of covalent attachment. Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.
应用
TopFluor™ PS may be used in liposome generation and as a synthetic fluorescent phosphoserine (PS) analogue to study PS distribution and dynamics in mouse embryonic fibroblasts (MEFs). It has also been used in the preparation of donor liposomes.
生化/生理作用
Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. PS actively participates in the locomotor functions, like rapid reactions and reflexes.
包装
5 mL Amber Glass Screw Cap Vial (810283P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Phosphatidylserine dynamics in cellular membranes
Kay JG, et al.
Molecular Biology of the Cell, 23(11), 2198-2212 (2012)
Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease
Hernandez-Alvarez MI, et al.
Cell, 177(4), 881-895 (2019)
Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies
Conrad KS, et al.
Nature Communications, 8(1908), 1-13 (2017)
Phosphatidylserine and the human brain
Glade MJ and Smith K
Nutrition, 31(6), 781-786 (2015)
Investigation of the biophysical properties of a fluorescently modified ceramide-1-phosphate
Shirey CM, et al.
Chemistry and Physics of Lipids, 200, 32-32 (2016)
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