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经验公式（希尔记法）:
C98H175BF2N4O18P2
化学文摘社编号:
分子量:
1808.21
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
TopFluor™ Cardiolipin, 1,1′,2,2′-tetraoleoyl cardiolipin[4-(dipyrrometheneboron difluoride)butanoyl] (ammonium salt) TopFluor™ Cardiolipin, chloroform
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810286C-100ug)
pkg of 1 × 1 mL (810286C-500ug)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810286C
concentration
0.1 mg/mL (810286C-100ug)
0.5 mg/mL (810286C-500ug)
shipped in
dry ice
storage temp.
−20°C
Packaging
5 mL Amber Glass Screw Cap Vial (810286C-500ug)
5 mL Amber Glass Screw Cap Vial (810286C-100ug)
General description
Cardiolipin, a unique phospholipid is present and synthesised in the inner mitochondrial membrane.
TopFluor™ cardiolipin is a fluorescent analog of the bioactive phospholipid, cardiolipin.
Biochem/physiol Actions
Cardiolipin is very much essential for the functional activity of several inner mitochondrial membrane proteins, like respiratory chain complexes. It participates in mitochondrial oxidative phosphorylation. It is also essential for proper functioning and structure of the inner mitochondrial membrane (IMM).
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Clyde A Daly et al.
Langmuir : the ACS journal of surfaces and colloids, 36(18), 5030-5039 (2020-04-18)
The composition, orientation, and conformation of proteins in biomolecular coronas acquired by nanoparticles in biological media contribute to how they are identified by a cell. While numerous studies have investigated protein composition in biomolecular coronas, relatively little detail is known
Functional role of cardiolipin in mitochondrial bioenergetics
Paradies G, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1837(4), 408-417 (2014)
Cintia Kawai et al.
The journal of physical chemistry. B, 118(41), 11863-11872 (2014-09-24)
Fluorescence quenching of lipid-bound pyrene was used to assess the binding of cytochrome c (cyt c) to liposomes that mimic the inner mitochondrial membrane (IMM) POPC/DOPE/TOCL, with the conditions that it did or did not contain oxidized phosphatidylcholine molecules, i.e.
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