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Merck
CN

810330C

Avanti

18:1 Dansyl PE

Avanti Research - A Croda Brand

别名:

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(5-dimethylamino-1-naphthalenesulfonyl) (ammonium salt)

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关于此项目

经验公式(希尔记法):
C53H92N3O10PS
化学文摘社编号:
分子量:
994.35
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

18:1 Dansyl PE, Avanti Research - A Croda Brand

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810330C-1mg)
pkg of 5 × 1 mL (810330C-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

1 mg/mL (810330C-1mg)
1 mg/mL (810330C-5mg)

lipid type

fluorescent lipids

shipped in

dry ice

storage temp.

−20°C

Application

18:1 Dansyl PE has been used in unilamellar liposome preparation. It may be used to incorporate into liposomes as the fluorescence energy transfer (FRET) acceptor. It may also be used as a component in Golgi-like acceptor liposomes for lipid transfer assay.

Biochem/physiol Actions

Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1).

General description

Phosphoethanolamine (PHOS) is a precursor to phosphatidylcholine and phosphatidylethanolamine. 18:1 Dansyl PE is a hygroscopic, light sensitive lipid.

Packaging

5 mL Amber Glass Screw Cap Vial (810330C-1mg)
5 mL Amber Glass Screw Cap Vial (810330C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

法规信息

易制毒化学品(2类)
危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Interaction of human chloride intracellular channel protein 1 (CLIC1) with lipid bilayers: a fluorescence study
Hare JE, et al.
Biochemistry, 55(27), 3825-3833 (2016)
Anshuman Mohapatra et al.
Biochemical and biophysical research communications, 521(3), 732-738 (2019-11-11)
The organization of caveolae ultrastructures in the plasma membrane and the functions they dictate are mediated by membrane-embedded caveolins (caveolin-1, 2, 3) and peripherally attached cavins (cavin-1, 2, 3, 4). Mutations in caveolin and cavin genes are associated with a
INAUGURAL ARTICLE by a Recently Elected Academy Member: Resistin-like molecule β is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium.
Propheter D C, et al.
Proceedings of the National Academy of Sciences of the USA, 114(42), 11027-11027 (2017)
Phosphoethanolamine and the danger of unproven drugs
Ponde N, et al.
Ecancermedicalscience, 10(7), 3658-3667 (2016)
Synthetic phosphoethanolamine: the state of the art of scientific production
Anastacio L de B, et al.
Brazilian Journal of Pharmaceutical Sciences , 53(4), 3658-3667 (2017)

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