跳转至内容
Merck
CN

810340P

Avanti

Click PI(4,5)P2-azido

Avanti Research - A Croda Brand

别名:

1-oleoyl-2-(6-(6-azidohexanoyl)aminohexanoyl)-sn-glycero-3-phosphoinositol-4.5-bisphosphate (ammonium salt)

登录 查看组织和合同定价。

选择尺寸


关于此项目

经验公式(希尔记法):
C39H82N7O20P3
化学文摘社编号:
分子量:
1062.02
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

Click PI(4,5)P2-azido, Avanti Research - A Croda Brand 810340P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (810340P-100ug))

manufacturer/tradename

Avanti Research - A Croda Brand 810340P

lipid type

click reagents

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is an anionic lipid  and is present in the plasma membrane (PM).

Biochem/physiol Actions

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a lipid messenger. It controls exocytosis, actin cytoskeleton dynamics and endocytosis. It also plays a key role in signal transduction, vesicle trafficking and motility. The azido functional group in the lipid may involve in a copper-catalyzed reaction to form click reaction.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (810340P-100ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助,请联系 客户支持

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Clickable lipids: azido and alkynyl fatty acids and triacylglycerols
Zerkowski JA, et al.
Journal of the American Oil Chemists' Society, 86(11), 1115-1115 (2009)
Xiaojun Tan et al.
Journal of cell science, 128(22), 4047-4056 (2015-11-18)
Phosphoinositides are a collection of lipid messengers that regulate most subcellular processes. Amongst the seven phosphoinositide species, the roles for phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] at the plasma membrane, such as in endocytosis, exocytosis, actin polymerization and focal adhesion assembly, have been
Analysis of Phosphatidic Acid Binding and Regulation of PIPKI In Vitro and in Intact Cells
Methods in Enzymology, 583, 359-374 (2017)
Arne Gericke et al.
Advances in experimental medicine and biology, 991, 85-104 (2013-06-19)
PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) is a relatively common anionic lipid that regulates cellular functions by multiple mechanisms. Hydrolysis of PtdIns(4,5)P2 by phospholipase C yields inositol trisphosphate and diacylglycerol. Phosphorylation by phosphoinositide 3-kinase yields PtdIns(3,4,5)P3, which is a potent signal for survival
Mira Sohn et al.
The Journal of cell biology, 217(5), 1797-1813 (2018-02-24)
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a critically important regulatory lipid of the plasma membrane (PM); however, little is known about how cells regulate PM PI(4,5)P2 levels. Here, we show that the phosphatidylinositol 4-phosphate (PI4P)/phosphatidylserine (PS) transfer activity of the endoplasmic reticulum

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持