810602P
Avanti
16:0-7 Doxyl PC
Avanti Research™ - A Croda Brand
别名:
1-palmitoyl-2-stearoyl-(7-doxyl)-sn-glycero-3-phosphocholine
产品名称
16:0-7 Doxyl PC, Avanti Research™ - A Croda Brand 810602P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810602P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810602P
脂质类型
ESR probes
phospholipids
运输
dry ice
储存温度
−20°C
一般描述
Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.
Phosphatidylcholine (PC), a strong bilayer-forming lipid is the most common phospholipid in mammalian membranes. Several prokaryotic and eukaryotic pathogens has phosphorylcholine as its structural constituent.
生化/生理作用
Phosphorylcholine (PC) possesses immunomodulatory properties.
包装
5 mL Clear Glass Sealed Ampule (810602P-1mg)
制备说明
Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
法规信息
新产品
此项目有
The Membranes of Cells (2016)
W Harnett et al.
Immunology today, 20(3), 125-129 (1999-04-22)
Phosphorylcholine (PC) is a structural component of a variety of prokaryotic and eukaryotic pathogens. In some cases, PC in infectious agents can benefit the infected host due to its targeting by both the innate and adaptive immune responses. However, as
Ultra-stable temperature control in EPR experiments: thermodynamics of gel-to-liquid phase transition in spin-labeled phospholipid bilayers and bilayer perturbations by spin labels
Alaouie AM, et. al.
Journal of Magnetic Resonance, 182, 229-238 (2006)
ESR of spin-labeled bacteriophage M13 coat protein in mixed phospholipid bilayers
de Jongh HH
Biochimica et Biophysica Acta, 1024, 82-88 (1990)
Insight into antibody combining sites using nuclear magnetic resonance and spin label haptens
McConnell HM
Advances in Protein Chemistry, 49, 135-148 (1996)
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