810603P
Avanti
16:0-10 Doxyl PC
Avanti Research™ - A Croda Brand
别名:
1-palmitoyl-2-stearoyl-(10-doxyl)-sn-glycero-3-phosphocholine
产品名称
16:0-10 Doxyl PC, Avanti Research™ - A Croda Brand 810603P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810603P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810603P
脂质类型
ESR probes
phospholipids
运输
dry ice
储存温度
−20°C
一般描述
Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.
Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine metabolism. 10-Doxyl is a spin label probe.
应用
16:0-10 Doxyl PC may be used:
- in vesicles for quenching PT-(1–46)F4W fluorescence
- as vesicle component for tryptophan based fluorescence emission studies
- to probe the oxygen and Ni[II] ethylenediaminediacetic acid (NiEdda) accessibilities inside liposomes
生化/生理作用
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.
包装
5 mL Clear Glass Sealed Ampule (810603P-1mg)
制备说明
Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
法规信息
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