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Merck
CN

810610P

Avanti

4-palmitamido-TEMPO

Avanti Research™ - A Croda Brand

别名:

4-Palmitamido-2,2,6,6-tetramethylpiperidine-1-oxyl; 2,2,6,6-Tetramethyl-4-[(1-oxohexadecyl)amino]-1-piperidinyloxy; 2,2,6,6-tetramethyl-4-palmitamidopiperidinooxy; 2,2,6,6-Tetramethylpalmitoylamidopiperidine-1-oxyl; 4-(Palmitylimino)-2,2,6,6-tetramethyl-1

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关于此项目

经验公式（希尔记法）:
C25H49N2O2
化学文摘社编号:
22977-65-7
分子量:
409.67
MDL number:
MFCD02259239
NACRES:
NA.25
UNSPSC Code:
12352211
Assay:
>99% (TLC)
Form:
powder

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产品名称

4-palmitamido-TEMPO, N-tempoyl palmitamide, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810610P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810610P

lipid type

ESR probes

shipped in

dry ice

storage temp.

−20°C

General description

4-palmitamido-TEMPO/N-tempoyl-palmitamide is a spin label, that is present in the polar head-group region of the membrane.
This amphiphilic compound binds strongly to membranes by virture of its long hydrocarbon chain, but the polarity of the amide linkage is expected to localize the nitroxide function in the aqueous phase adjacent to the membrane surface. The location of the nitroxide function allows one to investigate electrostatic potentials and lipid-protein interactions at the membrane surface.

Application

4-palmitamido-TEMPO/N-tempoyl palmitamide (N-TP) may be used:
  • to enrich rod outer segment (ROS) membranes
  • as a spin probe in vesicles/bilayer to prepare samples for electron spin resonance (ESR) experiments
  • as a component in liposomes to assess the mobility of lipid headgroups

Packaging

5 mL Amber Glass Screw Cap Vial (810610P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

历史批次信息供参考:

分析证书(COA)

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Ciara C M Lally et al.
Nature communications, 8, 14258-14258 (2017-02-22)
G-protein-coupled receptors are membrane proteins that are regulated by a small family of arrestin proteins. During formation of the arrestin-receptor complex, arrestin first interacts with the phosphorylated receptor C terminus in a pre-complex, which activates arrestin for tight receptor binding.
Shani Ben-Zichri et al.
Biochimica et biophysica acta. Biomembranes, 1861(1), 75-82 (2018-11-06)
Curcumin, the main molecular ingredient of the turmeric spice, has been reported to exhibit therapeutic properties for varied diseases and pathological conditions. While curcumin appears to trigger multiple signaling pathways, the precise mechanisms accounting for its therapeutic activity have not
Pavanjeet Kaur et al.
Biophysical journal, 110(8), 1789-1799 (2016-04-28)
γ-AApeptides are a new class of antibacterial peptidomimetics that are not prone to antibiotic resistance and are highly resistant to protease degradation. It is not clear how γ-AApeptides interact with bacterial membranes and alter lipid assembly, but such information is
Y K Shin et al.
Biophysical journal, 61(6), 1443-1453 (1992-06-01)
A new general method for the determination of electrostatic potentials at biological surfaces is presented. The approach is based on measurement of the collision frequency of a charged nitroxide in solution with a nitroxide fixed to the surface at the

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