产品名称
PAF（来自心脏PC）, Avanti Research™ - A Croda Brand 840009P, powder
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCC)=O
InChI
1S/C12H26NO7P/c1-6-17-9-12(20-11(2)14)10-19-21(15,16)18-8-7-13(3,4)5/h12H,6-10H2,1-5H3/t12-/m1/s1
InChI key
OLGKYSVSAKLUHK-GFCCVEGCSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (840009P-10mg), pkg of 1 × 25 mg (840009P-25mg), pkg of 1 × 5 mg (840009P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840009P
lipid type
phospholipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
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General description
血小板活化因子（PAF；1-O-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱）是一种内源性磷脂，由多个细胞合成。PAF是磷脂酰胆碱衍生物。
Biochem/physiol Actions
血小板活化因子（PAF；1-O-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱）与动脉血栓形成，内毒素性休克，急性炎症和急性过敏性疾病有关。它在人类结肠中作为溃疡性结肠炎和克罗恩′氏病发病机理的介质。还参与血小板活化和炎症。
Packaging
5 mL透明玻璃密封安瓿（840009P-10mg）
5 mL透明玻璃密封安瓿（840009P-25mg）
5 mL透明玻璃密封安瓿（840009P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
PAFAH Ib phospholipase A2 subunits have distinct roles in maintaining Golgi structure and function
Bechler ME and Brown WJ
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1831(3), 595-601 (2013)
Thromboxane A2-mediated Cl- secretion induced by platelet-activating factor in isolated rat colon
Suzuki T, et al.
European Journal of Pharmacology, 400(2-3), 297-303 (2000)
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