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Merck
CN

840030P

Avanti

06:0 PS

Avanti Research™ - A Croda Brand

别名:

PS(6:0/6:0)

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经验公式（希尔记法）:
C18H33NO10PNa
化学文摘社编号:
321862-85-5
分子量:
477.42
UNSPSC Code:
51191904
NACRES:
NA.25

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产品名称

06:0 PS, 1,2-dihexanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O.[Na+]

InChI

1S/C18H34NO10P.Na/c1-3-5-7-9-16(20)26-11-14(29-17(21)10-8-6-4-2)12-27-30(24,25)28-13-15(19)18(22)23;/h14-15H,3-13,19H2,1-2H3,(H,22,23)(H,24,25);/q;+1/p-1/t14-,15+;/m1./s1

InChI key

OPDYVXCKOQKYDZ-LIOBNPLQSA-M

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840030P-10mg)
pkg of 1 × 25 mg (840030P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840030P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

Application

06:0 PS may be used to study its effect on α-syn (α-synuclein) oligomerization by DA (dopamine) and as a phospholipid substrate to determine the kinetic parameters for phospholipase C by chromogenic assay. It has also been used in the preparation of phospholipid vesicles.

Biochem/physiol Actions

Phosphatidylserine (PS) participates in several signaling pathways. This membrane phospholipid controls the Akt (protein kinase B) phosphorylation process.

General description

Phosphatidylserine (PS) is an acidic phospholipid. Approximately 15–33 mol% of PS is present in the inner leaflet of the plasma membrane.

Packaging

5 mL Clear Glass Sealed Ampule (840030P-10mg)
5 mL Clear Glass Sealed Ampule (840030P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 223-249 (2008)
Akt-GSK3 beta Pro-survival Signaling Pathway in Cerebral Ischemic Injury
Primer on Kidney Diseases, Volume 953, 269-272 (2017)
Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 223-249 (2008)
Mingquan Guo et al.
Journal of molecular neuroscience : MN, 33(1), 67-73 (2007-09-29)
Phosphatidylserine (PS), the major acidic phospholipid class in eukaryotic biomembranes, plays an important role in various signaling pathways. We have previously demonstrated that docosahexaenoic acid (DHA, 22:6n-3) positively modulates PS biosynthesis and accumulation in neuronal cells, promoting survival. In this
Carolina Varela Chavez et al.
Cellular microbiology, 17(10), 1477-1493 (2015-04-18)
Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catalytic domain (TcsL-cat) into the cytosol upon an autoproteolytic process. TcsL-cat
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商品

Critical Micelle Concentrations (CMCs) - Avanti Research™ Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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