Merck
CN

840035C

Avanti

18:1 PS (DOPS)

Avanti Polar Lipids

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别名:
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); DOPS; PS(18:1(9Z)/18:1(9Z))
经验公式(希尔记法):
C42H77NO10PNa
CAS号:
分子量:
810.03
NACRES:
NA.25

描述

1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

检测方案

>99% (TLC)

形式

liquid

包装

pkg of 1 × 1 mL (840035C-10mg)
pkg of 1 × 2.5 mL (840035C-25mg)
pkg of 2 × 4 mL (840035C-200mg)
pkg of 5 × 4 mL (840035C-500mg)

manufacturer/tradename

Avanti Polar Lipids

浓度

10 mg/mL (840035C-10mg)
10 mg/mL (840035C-25mg)
25 mg/mL (840035C-200mg)
25 mg/mL (840035C-500mg)

lipid type

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1

InChI key

KPHZNDUWYZIXFY-YORIBCANSA-M

一般描述

DOPS is an excellent substitute for the naturally occurring Brain PS. It has similar physical properties and is more stable to oxidation. DOPS has been used, along with DOPC and DOPE, in lipid mixtures to mimic platelet membranes for coagulation studies.
Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules. 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) carry a carboxylic acid group and a protonated amine group in their head group.

应用

18:1 PS (DOPS) has been used as a component of supported membrane tubes (SMrT) templates. It has also been used in the preparation of lipid-mixing vesicles, content-mixing vesicles and lipid mixture.

生化/生理作用

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It plays a key role in the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

包装

30 mL Amber Narrow Mouth Bottle with Screw Cap (840035C-500mg)
5 mL Clear Glass Sealed Ampule (840035C-10mg)
5 mL Clear Glass Sealed Ampule (840035C-200mg)
5 mL Clear Glass Sealed Ampule (840035C-25mg)

通常也和此产品一起购买

产品编号
说明
价格

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

危险化学品
易制毒化学品(2类)

分析证书(COA)

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示例

T1503
货号
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25G
包装规格/数量

其它示例:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

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  • 如果您查询到的批号为 TO09019TO 等,请输入去除前两位字母的批号:09019TO。

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A single vesicle-vesicle fusion assay for in vitro studies of SNAREs and accessory proteins
Diao J, et al.
Nature Protocols, 7(5), 921-921 (2012)
Use of the supported membrane tube assay system for real time analysis of membrane fission reactions
Dar S, et al.
Nature Protocols, 12(2), 390-390 (2017)
Choosing the right fluorophore for single-molecule fluorescence studies in a lipid environment
Zhang Z, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(7), 1242- 1253 (2017)
Adsorption of O-phospho-L-serine and L-serine onto poorly crystalline apatite
Benaziz L, et al.
Journal of Colloid and Interface Science, 238(1), 48-53 (2001)
Alena Khmelinskaia et al.
Langmuir : the ACS journal of surfaces and colloids (2018-09-27)
DNA origami nanotechnology is being increasingly used to mimic membrane-associated biophysical phenomena. Although a variety of DNA origami nanostructures has already been produced to target lipid membranes, the requirements for membrane binding have so far not been systematically assessed. Here

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