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Merck
CN

840044C

Avanti

Soy PI

Avanti Research - A Croda Brand

别名:

L-α-phosphatidylinositol (Soy) (sodium salt)

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化学文摘社编号:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

Soy PI, Avanti Research - A Croda Brand 840044C

SMILES string

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP([O-])(OC[C@@]([H])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[Na+]

InChI

1S/C43H79O13P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(45)55-35(34-54-57(51,52)56-43-41(49)39(47)38(46)40(48)42(43)50)33-53-36(44)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35,38-43,46-50H,3-10,12,14-16,19-34H2,1-2H3,(H,51,52);/q;+1/p-1/b13-11-,18-17-;/t35-,38?,39-,40?,41?,42?,43-;/m1./s1

InChI key

DCDQYHYLAGWAPO-UQZYTPKFSA-M

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (840044C-10mg)
pkg of 1 × 2 mL (840044C-50mg)
pkg of 1 × 2.5 mL (840044C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 840044C

concentration

10 mg/mL (840044C-10mg)
10 mg/mL (840044C-25mg)
25 mg/mL (840044C-50mg)

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

Application

Soy PI has been used in PI 3-kinase assay.

Biochem/physiol Actions

L-α-phosphatidylinositol (Soy) acts as a cellular mediator in signal transduction processes. It is used to design therapeutic delivery vehicles for drug delivery. Soy PI also contributes to the regulation of cholesterol metabolism.

General description

L-α-phosphatidylinositol (Soy) is a naturally occurring, negatively charged glycerophospholipid with an inositol ring. It is found in biological membranes, which are involved in scaffolding, cellular compartmentalization and signal transduction.

Packaging

5 mL Clear Glass Sealed Ampule (840044C-10mg)
5 mL Clear Glass Sealed Ampule (840044C-25mg)
5 mL Clear Glass Sealed Ampule (840044C-50mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

易制毒化学品(2类)
危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Vps34 kinase domain dynamics regulate the autophagic PI 3-kinase complex
Stjepanovic G, et al.
Molecular Cell, 67(3), 528-534 (2017)
Phospholipids as cardiovascular therapeutics
Pandey NR and Sparks DL
Current Opinion in Investigational Drugs, 9(3), 281-285 (2008)
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
Aaron Peng et al.
Chemistry and physics of lipids, 165(1), 15-22 (2011-10-26)
Liposomes consisted of phosphatidylinositol (PI) and phosphatidylcholine (PC) have been utilized as delivery vehicle for drugs and proteins. In the present work, we studied the effect of soy PI on physical properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes such as phase state
Yoshiko Uchiyama et al.
Brain research, 1151, 46-54 (2007-04-06)
Membrane composition serves to identify intracellular compartments, signal cell death, as well as to alter a cell's electrical and physical properties. Here we use amperometry to show that supplementation with the phospholipids phosphatidylcholine (PC), phosphatidylethanolamine (PE), sphingomyelin (SM), and phosphatidylserine

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