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Merck
CN

840044P

Avanti

大豆 PI

Avanti Research™ - A Croda Brand

别名:

L-α-磷脂酰肌醇(大豆) （钠盐）

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关于此项目

化学文摘社编号:
383907-36-6
MDL number:
MFCD00145109
UNSPSC Code:
12352211
NACRES:
NA.25

主要文件

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产品名称

大豆 PI, Avanti Research™ - A Croda Brand

SMILES string

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP([O-])(OC[C@@]([H])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[Na+]

InChI

1S/C43H79O13P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(45)55-35(34-54-57(51,52)56-43-41(49)39(47)38(46)40(48)42(43)50)33-53-36(44)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35,38-43,46-50H,3-10,12,14-16,19-34H2,1-2H3,(H,51,52);/q;+1/p-1/b13-11-,18-17-;/t35-,38?,39-,40?,41?,42?,43-;/m1./s1

InChI key

DCDQYHYLAGWAPO-UQZYTPKFSA-M

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840044P-10mg)
pkg of 2 × 100 mg (840044P-200mg)
pkg of 1 × 25 mg (840044P-25mg)
pkg of 1 × 50 mg (840044P-50mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

相关类别

Application

大豆PI已用于制备脂质体。

Biochem/physiol Actions

Lα-磷脂酰肌醇（大豆）在信号转导过程中起着细胞介质的关键作用。它用于设计药物递送的治疗性递送载体。大豆PI还有助于调节胆固醇代谢。

General description

Lα-磷脂酰肌醇（大豆）是带负电荷的天然存在的带有肌醇环的甘油磷脂。它存在于生物膜中，参与支架、细胞区室化和信号转导。

Packaging

5 mL透明玻璃密封安瓿（840044P-10mg）
5 mL透明玻璃密封安瓿（840044P-200mg）
5 mL透明玻璃密封安瓿（840044P-25mg）
5 mL透明玻璃密封安瓿（840044P-50mg）

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Phospholipids as cardiovascular therapeutics
Pandey NR and Sparks DL
Current Opinion in Investigational Drugs, 9(3), 281-285 (2008)
Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.
Sevova ES, et al.
The Journal of Biological Chemistry, 285(27), 20580-20587 (2010)
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
Aaron Peng et al.
Chemistry and physics of lipids, 165(1), 15-22 (2011-10-26)
Liposomes consisted of phosphatidylinositol (PI) and phosphatidylcholine (PC) have been utilized as delivery vehicle for drugs and proteins. In the present work, we studied the effect of soy PI on physical properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes such as phase state
Ashutosh Tripathi et al.
The Journal of biological chemistry, 294(50), 19081-19098 (2019-11-07)
Phosphatidylinositol-transfer proteins (PITPs) are key regulators of lipid signaling in eukaryotic cells. These proteins both potentiate the activities of phosphatidylinositol (PtdIns) 4-OH kinases and help channel production of specific pools of phosphatidylinositol 4-phosphate (PtdIns(4)P) dedicated to specific biological outcomes. In
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