产品名称
Heart PC, Avanti Research™ - A Croda Brand 840052P, powder
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
InChI key
JLPULHDHAOZNQI-ZTIMHPMXSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 2 × 100 mg (840052P-200mg)
pkg of 1 × 25 mg (840052P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840052P
lipid type
phosphoglycerides
phospholipids
shipped in
dry ice
storage temp.
−20°C
Application
Heart PC has been used in the preparation of phospholipid reference mixture.
Biochem/physiol Actions
Phosphatidylcholine (PC) in the liver is responsible for the production of very low density lipoproteins (VLDL). It is an important source for the formation of lipid mediators and secondary messengers.
General description
Contains ~40% plasmalogen ether lipid
Phosphatidylcholine (PC) is a glycerophospholipid present abundantly in eukaryotes. It comprises 40-50% of the total phospholipid content in the cell membrane. PC is synthesized by the Kennedy pathway.
Packaging
5 mL Clear Glass Sealed Ampule (840052P-200mg)
5 mL Clear Glass Sealed Ampule (840052P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5(6), 16787-16787 (2015)
Expression of Shiga toxin 2e glycosphingolipid receptors of primary porcine brain endothelial cells and toxin-mediated breakdown of the blood-brain barrier
Meisen I, et al.
Glycobiology, 23(6), 745-759 (2013)
The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease.
van der Veen J N, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(9 Pt B), 1558-1558 (2017)
Marianne S Jurkowitz et al.
Biochimica et biophysica acta, 1848(2), 742-751 (2014-12-03)
Lysoplasmalogenase catalyzes hydrolytic cleavage of the vinyl-ether bond of lysoplasmalogen to yield fatty aldehyde and glycerophospho-ethanolamine or glycerophospho-choline. We recently purified lysoplasmalogenase from rat liver microsomes and identified the protein as TMEM86B, an integral membrane protein that is a member
Ivan U Kouzel et al.
Journal of lipid research, 54(3), 692-710 (2012-12-19)
Glycosphingolipids (GSLs) of the globo-series constitute specific receptors for Shiga toxins (Stxs) released by certain types of pathogenic Escherichia coli strains. Stx-loaded leukocytes may act as transporter cells in the blood and transfer the toxin to endothelial target cells. Therefore
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