产品名称
Brain PC, Avanti Research™ - A Croda Brand 840053P, powder
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
InChI key
WTJKGGKOPKCXLL-VYOBOKEXSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 2 × 100 mg (840053P-200mg)
pkg of 1 × 25 mg (840053P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840053P
shipped in
dry ice
storage temp.
−20°C
Application
Brain PC is suitable for use:
- in the preparation of small unilamellar vesicles (SUVs)
- as a constituent in serial protein misfolding cyclic amplification (sPMCA) buffer
- as standard for ion mobility shift-mass spectrometry (IMS-MS)
Biochem/physiol Actions
Phosphatidylcholine (PC) is the major source of choline through food supplements. PC helps in improving learning and memory. PC functions in membrane fusion and transport and endocytosis. It is implicated in lowering of blood lipid and cholesterol levels, preventing cardiovascular disease and inhibiting obesity.
General description
Phosphatidylcholine (PC) is an important structural component of cell membrane and plasma lipoprotein. It is synthesized by CDP choline pathway. Liver is the main site for the synthesis of PC. Brain PC predominantly contains PC 16:0/16:0 and PC 16:0/18:1.
Packaging
5 mL Clear Glass Sealed Ampule (840053P-200mg)
5 mL Clear Glass Sealed Ampule (840053P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine.
Zhou MM, et al.
Lipids in Health and Disease, 15(1), 135-135 (2016)
Requirements for mutant and wild-type prion protein misfolding in vitro.
Noble GP, et al.
Biochemistry, 54(5), 1180-1187 (2015)
Choline, Phospholipids, Health, and Disease (1998)
The membrane lipid phosphatidylcholine is an unexpected source of triacylglycerol in the liver.
van der Veen JN, et al.
The Journal of Biological Chemistry, 287(28), 23418-23426 (2012)
Using supported bilayers to study the spatiotemporal organization of membrane-bound proteins.
Methods in Cell Biology, 128, 223-241 (2015)
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