产品名称
氢化磷脂酰胆碱, Avanti Research™ - A Croda Brand
SMILES string
[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C
InChI
1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
InChI key
NRJAVPSFFCBXDT-HUESYALOSA-N
description
L-α-phosphatidylcholine, hydrogenated (Soy)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (840058P-1g)
pkg of 1 × 200 mg (840058P-200mg)
pkg of 1 × 25 mg (840058P-25mg)
pkg of 1 × 500 mg (840058P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
Packaging
60 mL琥珀色宽口螺旋盖瓶（840058P-1g）
30 mL琥珀色宽口螺旋盖瓶（840058P-500mg）
5 mL琥珀色玻璃螺旋盖小瓶（840058P-200mg）
5 mL琥珀色玻璃螺旋盖小瓶（840058P-25mg）
Application
氢化L-α-磷脂酰胆碱（大豆）可用于生成脂质体，以重建补体活性人血浆、 布比卡因 和地塞米松的载量。
Biochem/physiol Actions
氢化L-α磷脂酰胆碱（Soy）天然存在，主要用于合成脂质体。它还用于合成小型单层囊泡（small unilamellar vesicle，SUV）。
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes
Graham SM, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 178(10), 101-107 (2014)
Ankita Dadwal et al.
Journal of microencapsulation, 1-14 (2020-04-16)
Aim: The aim of this project is to improve the therapeutic effectiveness, permeation and retention of clobetasol propionate in sebaceous glands by reporting the use of Squarticles as lipidic nanosystem.Methods: Homogenisation method is used for the formulation of Squarticles (nanoemulgel)
Mengting Lin et al.
Molecular pharmaceutics, 17(2), 499-506 (2019-12-12)
Nitrogen mustard (NM) is among the earliest drugs used to treat malignant tumors and it kills tumor cells by cross-linking DNA. Unfortunately, because of the short half-life and unfavorable selectivity, NM causes significant damage to normal tissues. As NM can
Establishing Liposome-Immobilized Dexamethasone-Releasing PDMS Membrane for the Cultivation of Retinal Pigment Epithelial Cells and Suppression of Neovascularization
Lin TW, et al.
International Journal of Molecular Sciences, 20(2), 241-241 (2019)
Nikolaos Naziris et al.
International journal of pharmaceutics, 574, 118849-118849 (2019-11-24)
The utilization of liposomes in biomedical applications has greatly benefited the diagnosis and treatment of various diseases. These biomimetic nano-entities have been very useful in the clinical practice as drug delivery systems in their conventional form, comprising lipids as structural
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