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Merck
CN

840058P

Avanti

氢化磷脂酰胆碱

Avanti Research - A Croda Brand

别名:

HSPC

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关于此项目

化学文摘社编号:
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
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描述

L-α-phosphatidylcholine, hydrogenated (Soy)

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 1 g (840058P-1g)
pkg of 1 × 200 mg (840058P-200mg)
pkg of 1 × 25 mg (840058P-25mg)
pkg of 1 × 500 mg (840058P-500mg)

制造商/商品名称

Avanti Research - A Croda Brand

脂质类型

phospholipids
phosphoglycerides

运输

dry ice

储存温度

−20°C

SMILES字符串

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChI key

NRJAVPSFFCBXDT-HUESYALOSA-N

应用

氢化L-α-磷脂酰胆碱(大豆)可用于生成脂质体,以重建补体活性人血浆、 布比卡因 和地塞米松的载量。

生化/生理作用

氢化L-α磷脂酰胆碱(Soy)天然存在,主要用于合成脂质体。它还用于合成小型单层囊泡(small unilamellar vesicle,SUV)。

包装

30 mL琥珀色宽口螺旋盖瓶(840058P-500mg)
5 mL琥珀色玻璃螺旋盖小瓶(840058P-200mg)
5 mL琥珀色玻璃螺旋盖小瓶(840058P-25mg)
60 mL琥珀色宽口螺旋盖瓶(840058P-1g)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nikolaos Naziris et al.
International journal of pharmaceutics, 574, 118849-118849 (2019-11-24)
The utilization of liposomes in biomedical applications has greatly benefited the diagnosis and treatment of various diseases. These biomimetic nano-entities have been very useful in the clinical practice as drug delivery systems in their conventional form, comprising lipids as structural
alginate encapsulation for bupivacaine delivery and mesenchymal stromal cell immunomodulatory cotherapy
Davis MS, et al
Journal of Inflammation Research, 12(10), 87-87 (2019)
Ankita Dadwal et al.
Journal of microencapsulation, 1-14 (2020-04-16)
Aim: The aim of this project is to improve the therapeutic effectiveness, permeation and retention of clobetasol propionate in sebaceous glands by reporting the use of Squarticles as lipidic nanosystem.Methods: Homogenisation method is used for the formulation of Squarticles (nanoemulgel)
Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes
Graham SM, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 178(10), 101-107 (2014)
Mengting Lin et al.
Molecular pharmaceutics, 17(2), 499-506 (2019-12-12)
Nitrogen mustard (NM) is among the earliest drugs used to treat malignant tumors and it kills tumor cells by cross-linking DNA. Unfortunately, because of the short half-life and unfavorable selectivity, NM causes significant damage to normal tissues. As NM can

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