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Merck
CN

840101C

Avanti

Egg PA

Avanti Research™ - A Croda Brand

别名:

L-α-phosphatidic acid (Egg, Chicken) (sodium salt)

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关于此项目

CAS Number:
383907-53-7
MDL编号:
MFCD00672609
UNSPSC代码:
12352211
NACRES:
NA.25

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方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (840101C-25mg)

制造商/商品名称

Avanti Research™ - A Croda Brand

浓度

10 mg/mL (840101C-25mg)

脂质类型

phosphoglycerides

运输

dry ice

储存温度

−20°C

SMILES字符串

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)O

InChI

1S/C37H71O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,35H,3-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b18-17-;/t35-;/m1./s1

InChI key

PPYXMAJBOKWTQX-RYRMQHSSSA-M

相关类别

一般描述

Phosphatidic acid (PA) is synthesized by the action of phospholipase D (PLD) on glycerophospholipids and by phosphorylation of diacylglycerol (DAG) by DAG kinase.

应用

Egg PA has been used in SEIPEN binding studies. It is suitable for use in the preparation of liposomes and to deduce different species of phosphatidic acid from egg by liquid chromatography-mass spectroscopy (LC-MS) and least squares spectral resolution (LSSR) analysis.

生化/生理作用

Phosphatidic acid (PA) contributes to membrane biogenesis by involving in the synthesis of glycerophospholipids like phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol and phosphatidylserine. PA is implicated in cell signaling.

包装

5 mL Clear Glass Sealed Ampule (840101C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Brain Lipids in Synaptic Function and Neurological Disease: Clues to Innovative Therapeutic Strategies for Brain Disorders (2015)
Extension of least squares spectral resolution algorithm to high-resolution lipidomics data
Zeng YX, et al.
Analytica Chimica Acta, 914(8), 35-46 (2016)
The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans
Klopfenstein DR and Vale RD
Molecular Biology of the Cell, 15(8), 3729-3739 (2004)
Dieter R Klopfenstein et al.
Molecular biology of the cell, 15(8), 3729-3739 (2004-05-25)
UNC-104 (KIF1A) is a kinesin motor that transports synaptic vesicles from the neuronal cell body to the terminal. Previous in vitro studies have shown that a Dictyostelium relative of UNC-104 transports liposomes containing acidic phospholipids, but whether this interaction is
Anne Araye et al.
PloS one, 11(4), e0153401-e0153401 (2016-04-14)
Botulinum neurotoxin A (BoNT/A) is composed of three domains: a catalytic domain (LC), a translocation domain (HN) and a receptor-binding domain (HC). Like most bacterial toxins BoNT/A is an amphitropic protein, produced in a soluble form that is able to
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