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经验公式(希尔记法):
C40H74O8PNa
化学文摘社编号:
分子量:
736.97
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
18:1 Phosphatidylmethanol, 1,2-dioleoyl-sn-glycero-3-phosphomethanol (sodium salt), powder
SMILES string
[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC)OC
InChI
1S/C40H75O8P.Na/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-39(41)46-36-38(37-47-49(43,44)45-3)48-40(42)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2;/h18-21,38H,4-17,22-37H2,1-3H3,(H,43,44);/q;+1/p-1/b20-18-,21-19-;/t38-;/m1./s1
InChI key
VZVXMZAFOPVENO-MDTXTNHHSA-M
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (840420P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840420P
shipped in
dry ice
storage temp.
−20°C
General description
18:1 Phosphatidylmethanol (1,2-dioleoyl-sn-glycero-3-phosphomethanol) is a phospholipid which carries an anionic head group. It is categorized as an alkyl phosphate under lipd headgroup modified lipids.
Application
18:1 Phosphatidylmethanol (1,2-dioleoyl-sn-glycero-3-phosphomethanol) may be used in unilamellar vesicles for fluorescence quenching vesicle binding assay and as an internal standard in ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) analysis for the quantification of phosphatidylethanols (PEths) in whole blood, venous/capillary-dried blood spots (V-DBS and C-DBS).
Packaging
5 mL Clear Glass Sealed Ampule (840420P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Brian Jeppesen et al.
The Journal of biological chemistry, 283(10), 6126-6135 (2008-01-05)
Annexin V binds to membranes with very high affinity, but the factors responsible remain to be quantitatively elucidated. Analysis by isothermal microcalorimetry and calcium titration under conditions of low membrane occupancy showed that there was a strongly positive entropy change
Natalie Kummer et al.
Analytical and bioanalytical chemistry, 408(3), 825-838 (2015-11-26)
Phosphatidylethanol species (PEths) are promising biomarkers of alcohol consumption. Here, we report on the set-up, validation, and application of a novel UHPLC-ESI-MS/MS method for the quantification of PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 in whole blood (30 μL) and
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