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Merck
CN

840433P

Avanti

08:0 PG

Avanti Research™ - A Croda Brand

别名:

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder, PG(8:0/8:0)

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关于此项目

经验公式（希尔记法）:
C22H42O10PNa
化学文摘社编号:
322647-21-2
分子量:
520.53
MDL number:
MFCD00674287
UNSPSC Code:
51191904
NACRES:
NA.25

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产品名称

08:0 PG, Avanti Research™ - A Croda Brand

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]

InChI

1S/C22H43O10P.Na/c1-3-5-7-9-11-13-21(25)29-17-20(32-22(26)14-12-10-8-6-4-2)18-31-33(27,28)30-16-19(24)15-23;/h19-20,23-24H,3-18H2,1-2H3,(H,27,28);/q;+1/p-1/t19?,20-;/m1./s1

InChI key

RMRPSQXPMWXLAU-TVEITMRYSA-M

description

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840433P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

Application

08:0 PG (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used as a short-/odd-fatty acyl chain analog to spike the lipid mixture for the quantification of a natural lipid mixture (egg PG).

Biochem/physiol Actions

Phosphatidylglycerol (PG) can serve as a specific ligand for 4E10 (neutralizing antibody) in the crystal structures. 08:0 PG serves as cryoprotectant in crystallization studies.

General description

Phosphatidylglycerol (PG) carries one phosphate in its headgroup and has two acyl chains, that are esterified to a glycerol. Hence it carry a negative charge.

Packaging

5 mL Clear Glass Sealed Ampule (840433P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lipid-Protein Interactions in Membranes
The Membranes of Cells (2016)
Adriana Irimia et al.
Immunity, 44(1), 21-31 (2016-01-19)
Numerous studies of the anti-HIV-1 envelope glycoprotein 41 (gp41) broadly neutralizing antibody 4E10 suggest that 4E10 also interacts with membrane lipids, but the antibody regions contacting lipids and its orientation with respect to the viral membrane are unknown. Vaccine immunogens
Tommy Hofmann et al.
Chemistry and physics of lipids, 223, 104782-104782 (2019-06-10)
In recent years, lipid quantification gained importance. In most cases, this is achieved by spiking the lipid mixture with deuterated standard lipids or lipid analogues that differ in chain length when compared with the natural lipid components. Usually, conventional ESI

商品

Critical Micelle Concentrations (CMCs) - Avanti Research™ Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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