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文件

840433P

Avanti

08:0 PG

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder

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别名:
PG(8:0/8:0)
经验公式（希尔记法）:
C22H42O10PNa
CAS号:
322647-21-2
分子量:
520.53
NACRES:
NA.25

检测方案

>99% (TLC)

形式

powder

包装

pkg of 1 × 10 mg (840433P-10mg)

制造商/商品名称

Avanti Polar Lipids 840433P

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]

InChI

1S/C22H43O10P.Na/c1-3-5-7-9-11-13-21(25)29-17-20(32-22(26)14-12-10-8-6-4-2)18-31-33(27,28)30-16-19(24)15-23;/h19-20,23-24H,3-18H2,1-2H3,(H,27,28);/q;+1/p-1/t19?,20-;/m1./s1

InChI key

RMRPSQXPMWXLAU-TVEITMRYSA-M

一般描述

Phosphatidylglycerol (PG) carries one phosphate in its headgroup and has two acyl chains, that are esterified to a glycerol. Hence it carry a negative charge.

应用

08:0 PG (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used as a short-/odd-fatty acyl chain analog to spike the lipid mixture for the quantification of a natural lipid mixture (egg PG).

生化/生理作用

Phosphatidylglycerol (PG) can serve as a specific ligand for 4E10 (neutralizing antibody) in the crystal structures. 08:0 PG serves as cryoprotectant in crystallization studies.

包装

5 mL Clear Glass Sealed Ampule (840433P-10mg)

储存分类代码

11 - Combustible Solids

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Lipid-Protein Interactions in Membranes
The Membranes of Cells (2016)
Adriana Irimia et al.
Immunity, 44(1), 21-31 (2016-01-19)
Numerous studies of the anti-HIV-1 envelope glycoprotein 41 (gp41) broadly neutralizing antibody 4E10 suggest that 4E10 also interacts with membrane lipids, but the antibody regions contacting lipids and its orientation with respect to the viral membrane are unknown. Vaccine immunogens
Tommy Hofmann et al.
Chemistry and physics of lipids, 223, 104782-104782 (2019-06-10)
In recent years, lipid quantification gained importance. In most cases, this is achieved by spiking the lipid mixture with deuterated standard lipids or lipid analogues that differ in chain length when compared with the natural lipid components. Usually, conventional ESI

商品

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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