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经验公式（希尔记法）:
C27H52O8PNa
化学文摘社编号:
分子量:
558.66
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
12:0 PA, 1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt), powder
SMILES string
[H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]
InChI
1S/C27H53O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-26(28)33-23-25(24-34-36(30,31)32)35-27(29)22-20-18-16-14-12-10-8-6-4-2;/h25H,3-24H2,1-2H3,(H2,30,31,32);/q;+1/p-1/t25-;/m1./s1
InChI key
CIOHBYXGWWPOIS-VQIWEWKSSA-M
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (840635P-200mg)
pkg of 1 × 25 mg (840635P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 840635P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
Application
12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt)) has been used as an internal lipid standard in the matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis. It may be used as a lipid standard:
- for the quantification of phospholipids by high-performance liquid chromatography coupled to tandem mass spectrometryelectrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
- for the quantification of lipids in cold-pressed rapeseed oils based on direct infusion electrospray ionization tandem mass spectrometry
- in liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis
Biochem/physiol Actions
Phosphatidic acid (PA) might serve as a modulator of phagocyte respiratory burst.
General description
12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate) is a sodium salt of modified lipid, wherein C-1, C-2 of glycerol is substituted with didodecanoyl and C-3 of glycerol is substituted with phosphatidic acid group.
Packaging
5 mL Amber Glass Screw Cap Vial (840635P-200mg)
5 mL Amber Glass Screw Cap Vial (840635P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Marie Garnier-Lhomme et al.
PloS one, 4(1), e4255-e4255 (2009-01-24)
The cytoplasm of eukaryotic cells is a highly dynamic compartment where membranes readily undergo fission and fusion to reorganize the cytoplasmic architecture, and to import, export and transport various cargos within the cell. The double membrane of the nuclear envelope
Richard D Byrne et al.
Cellular signalling, 19(5), 913-922 (2006-12-23)
Nuclear envelope assembly is an essential event in each cell cycle but the proteins and lipids involved in its regulation remain mostly unknown. Assembly involves membrane fusions but neither specific SNAREs nor Rab GTPases have been identified in its control.
Glycerolipids in signal transduction
New comprehensive biochemistry, 31, 237-255 null
Ya Xie et al.
Food chemistry, 285, 194-203 (2019-02-25)
Microwave pretreatment of rapeseeds prior to cold-pressing is a simple and desirable method for producing high quality oils. In this study, a rapid and sensitive lipid profiling platform employing an accurate quantification strategy was established based on direct infusion electrospray
Yuchen Sun et al.
Metabolites, 9(11) (2019-11-07)
Extracellular vesicles (EVs) consist of lipid bilayers, occur in various biofluids, and are invaluable in biomarker screening. Liquid chromatography coupled with high-resolution mass spectrometry (LC-MS) was recently used to study comprehensive EV lipid profiles in vitro. The aim of this
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