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关于此项目
经验公式(希尔记法):
C39H72O8PNa
化学文摘社编号:
分子量:
722.95
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
InChI
1S/C39H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,37H,3-16,21-36H2,1-2H3,(H2,42,43,44);/q;+1/p-1/b19-17-,20-18-;/t37-;/m1./s1
InChI key
JUKKLZHXFHPJSF-ZBFGHDQJSA-M
SMILES string
[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
description
1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (840875P-1g), pkg of 2 × 100 mg (840875P-200mg), pkg of 5 × 100 mg (840875P-500mg), pkg of 1 × 25 mg (840875P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
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General description
18:1 PA (1,2-二油酰-sn-丙三醇-3-磷酸盐(钠盐))是阴离子脂质。
Application
18:1 PA (1,2-二油酰-sn-丙三醇-3-磷酸盐(钠盐)):
- 可作为脂质体用于脂质体渗漏试验
- 可用于创建脂质体模板,以便合成磷酸钙(CaP)纳米壳
- 可用作脂质体/脂双层成分
- 作为神经元神经胶质培养基添加剂,用于研究星形胶质细胞磷脂酶D1 (PLD1)对于树枝状分支的作用
- 用于细胞色素c Trp59的化学发光试验
Biochem/physiol Actions
磷脂酸(PA)起脂质信使作用。
Packaging
5 mL 透明玻璃密封安瓿 (840875P-200 mg)
5 mL 透明玻璃密封安瓿 (840875P-25 mg)
5 mL 透明玻璃密封安瓿 (840875P-500 mg)
60 mL 琥珀色广口螺旋盖玻璃瓶 (840875P-1g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Comparison of DOPA and DPPA liposome templates for the synthesis of calcium phosphate nanoshells
Yeo CH, et al.
Ceramics International, 38(1), 561-570 null
Xinhui Sun et al.
Cell cycle (Georgetown, Tex.), 14(5), 721-731 (2015-01-16)
It had been known for decades that primordial follicles in mammalian ovaries are assembled with definite numbers and represent the ovarian reserve throughout the reproductive life. Intra-oocyte PI3K/mTOR pathways have been indicated to play a central role on the activation
Shutao Guo et al.
Journal of controlled release : official journal of the Controlled Release Society, 174, 137-142 (2013-11-28)
The poor solubility of cisplatin (CDDP) often presents a major obstacle in the formulation of CDDP in nanoparticles (NPs) by traditional methods. We have developed a novel method for synthesizing CDDP NPs taking advantage of its poor solubility. By mixing
Kathleen Frondorf et al.
The Journal of biological chemistry, 285(21), 15837-15847 (2010-03-23)
Phosphatidic acid (PA) is a pleiotropic lipid second messenger in mammalian cells. We report here that extracellular PA acts as a leukocyte chemoattractant, as membrane-soluble dioleoyl-PA (DOPA) elicits actin polymerization and chemotaxis of human neutrophils and differentiated proleukemic HL-60 cells.
Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds.
Reika Tei et al.
The Journal of cell biology, 219(3) (2020-01-31)
Phosphatidic acid (PA) is both a central phospholipid biosynthetic intermediate and a multifunctional lipid second messenger produced at several discrete subcellular locations. Organelle-specific PA pools are believed to play distinct physiological roles, but tools with high spatiotemporal control are lacking
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