InChI key
FJXDNGDRHUDFST-XQYKCTAGSA-M
SMILES string
[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (841138C-25mg), pkg of 2 × 4 mL (841138C-200mg), pkg of 5 × 4 mL (841138C-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
10 mg/mL (841138C-25mg), 25 mg/mL (841138C-200mg), 25 mg/mL (841138C-500mg)
lipid type
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphatidylglycerol (PG) is one of the major phospholipids in food and biological tissues. PG is the anionic phospholipid in the membranes of Staphylococcus sp. and Escherichia coli. PG is present in low amounts in mammalian membranes. Structurally, PG has two acyl chains esterified to a glycerol, bonded to a headgroup structure that has phosphate and carries negative charge. PG is synthesized from cytidine phosphate-diacylglycerol (CDP-DAG).
Application
Egg PG has been used:
- as a phospholipid to test the binding ability of SEIPIN, an integral membrane protein of endoplasmic recticulum
- as a standard for photodynamic treatment
- as a standard for the identification of phospholipids by thin layer chromatography and electrospray ionization-mass spectra (ESI-MS)
Biochem/physiol Actions
Phosphatidylglycerol (PG) is present in amniotic fluid and indicates fetal lung maturity. It functions as a precursor for cardiolipin in animals. In plants, PG is present in thylakoid membranes and plays a central role in photosynthesis.
Packaging
5 mL Clear Glass Sealed Ampule (841138C-200mg)
5 mL Clear Glass Sealed Ampule (841138C-25mg)
5 mL Clear Glass Sealed Ampule (841138C-500mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Liver,Kidney, Respiratory system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Photodynamic oxidation of Escherichia coli membrane phospholipids: new insights based on lipidomics
Alves E, et al.
Rapid Communications in Mass Spectrometry, 27(23), 2717-2728 (2013)
The
The Membranes of Cells, 27(23) (2016)
The
An Introduction to Biological Membranes: Composition, Structure and Function, 91(3) (2016)
Validation of an LC-MS/MS method for the quantification of choline-related compounds and phospholipids in foods and tissues
Xiong Y, et al.
Journal of Chromatography. B, Biomedical Applications, 911, 170-179 (2012)
Célia Jacoberger-Foissac et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 152, 348-357 (2020-06-02)
Liposomes are powerful tools for the optimization of peptides and adjuvant composition in cancer vaccines. Here, we take advantage of a liposomal platform versatility to develop three vaccine candidates associating a peptide from HA influenza virus protein as CD4 epitope
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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