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Merck
CN

850156P

Avanti

18:1 PI(3,4,5)P3

Avanti Research™ - A Croda Brand

别名:

1,2-二-(9Z-十八烯酰基)-sn-甘油-3- [磷酸肌醇-3,4,5-三磷酸]（铵盐）; PIP3[3′,4′,5′](18:1(9Z)/18:1(9Z))

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关于此项目

经验公式（希尔记法）:
C45H98N4O22P4
CAS Number:
799268-57-8
分子量:
1171.17
UNSPSC代码:
51191904
NACRES:
NA.25

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Product Name

18:1 PI(3,4,5)P3, 1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 100 μg (with stopper and crimp cap (850156P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850156P-500ug))

制造商/商品名称

Avanti Research™ - A Croda Brand 850156P

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]

InChI key

CTYBALUTLRWYAN-CJXCTDJBSA-N

相关类别

一般描述

磷脂酰肌醇是一种结构性磷脂。磷脂酰肌醇磷酸（PIP）位于质膜中。
肌醇磷脂物质是膜结合的信号分子，它参与细胞生理学的几乎所有方面，包括细胞生长、代谢、增殖和存活。

应用

18：1 PI（3,4,5）P3 适合用于脂质原液的制备以形成混合胶束。它也已用于：
  • 制备平面支撑脂质双层（SLB）
  • 补充或丰富吞噬细胞膜
  • 制备脂质体

生化/生理作用

与甘油磷脂相比，含磷酸肌醇的鞘脂可以以较低的水平诱导 ATPase。

包装

带塞子和压接盖的2 mL琥珀色精华瓶（850156P-100ug）
带塞子和压接盖的2 mL琥珀色精华瓶（850156P-500ug）

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Protein kinase Czeta exhibits constitutive phosphorylation and phosphatidylinositol-3, 4, 5-triphosphate-independent regulation
Tobias IS, et al.
The Biochemical Journal, 473(4), 509-523 (2016)
Phosphatidylinositol Turnover and Receptors
Ramazzotti G, et al.
Archives of Biochemistry and Biophysics (2016)
Rays H Y Jiang et al.
Cell host & microbe, 11(2), 99-100 (2012-02-22)
Survival of blood stage malaria parasites requires extensive host cell remodeling, which is facilitated by secretion of parasite proteins via a dedicated protein export pathway. In a recent Cell paper, Bhattacharjee et al., (2012) describe PI(3)P binding as one of the
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Membraneless organelles formed by liquid-liquid phase separation are dynamic structures that are employed by cells to spatiotemporally regulate their interior. Indeed, complex coacervation-based phase separation is involved in a multitude of biological tasks ranging from photosynthesis to cell division to
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