产品名称
08:0 PI, 1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 μg (with stopper and crimp cap (850181P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850181P-500ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 850181P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]
InChI
1S/C25H47O13P.H3N/c1-3-5-7-9-11-13-18(26)35-15-17(37-19(27)14-12-10-8-6-4-2)16-36-39(33,34)38-25-23(31)21(29)20(28)22(30)24(25)32;/h17,20-25,28-32H,3-16H2,1-2H3,(H,33,34);1H3/t17-,20-,21-,22+,23-,24-,25-;/m1./s1
InChI key
BJQNDQRSJKQZAM-RGISUMIPSA-N
General description
磷脂酰肌醇（PI）是一种甘油磷脂，具有带有环己醇部分的头基。08:1 PI（1,2-二辛酰基-sn-甘油-3-磷酸-（1′-肌醇））是具有较短酰基链的PI类似物。
Application
08:0 PI（1，2-二辛酰基-sn-甘油-3-磷酸-（1′-肌醇））可以用于：
- 作为磷脂酰-肌醇甘露糖基转移酶（PimA）的底物来比较非底物磷脂对活性的效应
- 在酶促测定中替代分枝杆菌膜以测量PimA活性
- 作为离子阱飞行时间（IT-TOF）系统中的磷脂（PL）标准品，以研究独特PL的断裂原理，也用作坚果样品中PL定量分析的非内源PL标准品
Biochem/physiol Actions
磷脂酰肌醇（PI）充当磷酸肌醇（一类信号脂质）的前体。
肌醇磷脂物质是膜结合的信号分子，它参与细胞生理学的几乎所有方面，包括细胞生长、代谢、增殖和存活。
Packaging
带塞子和压接盖的2 mL棕色血清瓶（850181P-100ug）
带塞子和压接盖的2 mL棕色血清瓶（850181P-500ug）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
Endocytosis and the Endosomal Membrane System
Cell Biology, 377-392 (2017)
Inhibition of Phosphoinositide 3-Kinase and Acquired Long QT Syndrome
Cardiac Electrophysiology: From Cell to Bedside, 106-112 (2018)
Marcelo E Guerin et al.
The Journal of biological chemistry, 282(28), 20705-20714 (2007-05-19)
Mycobacterial phosphatidylinositol mannosides (PIMs) and metabolically derived cell wall lipoglycans play important roles in host-pathogen interactions, but their biosynthetic pathways are poorly understood. Here we focus on Mycobacterium smegmatis PimA, an essential enzyme responsible for the initial mannosylation of phosphatidylinositol.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 850181P-100UG | 04061835229772 |
| 850181P-500UG | 04061835229789 |