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Merck
CN

850181P

Avanti

08:0 PI

Avanti Research™ - A Croda Brand

别名:

PI(8:0/8:0)

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关于此项目

经验公式（希尔记法）:
C25H50NO13P
化学文摘社编号:
2260795-76-2
分子量:
603.64
UNSPSC Code:
51191904
NACRES:
NA.25

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产品名称

08:0 PI, 1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

InChI

1S/C25H47O13P.H3N/c1-3-5-7-9-11-13-18(26)35-15-17(37-19(27)14-12-10-8-6-4-2)16-36-39(33,34)38-25-23(31)21(29)20(28)22(30)24(25)32;/h17,20-25,28-32H,3-16H2,1-2H3,(H,33,34);1H3/t17-,20-,21-,22+,23-,24-,25-;/m1./s1

InChI key

BJQNDQRSJKQZAM-RGISUMIPSA-N

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850181P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850181P-500ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 850181P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

相关类别

Application

08:0 PI（1，2-二辛酰基-sn-甘油-3-磷酸-（1′-肌醇））可以用于：
  • 作为磷脂酰-肌醇甘露糖基转移酶（PimA）的底物来比较非底物磷脂对活性的效应
  • 在酶促测定中替代分枝杆菌膜以测量PimA活性
  • 作为离子阱飞行时间（IT-TOF）系统中的磷脂（PL）标准品，以研究独特PL的断裂原理，也用作坚果样品中PL定量分析的非内源PL标准品

Biochem/physiol Actions

磷脂酰肌醇（PI）充当磷酸肌醇（一类信号脂质）的前体。
肌醇磷脂物质是膜结合的信号分子，它参与细胞生理学的几乎所有方面，包括细胞生长、代谢、增殖和存活。

General description

磷脂酰肌醇（PI）是一种甘油磷脂，具有带有环己醇部分的头基。08:1 PI（1,2-二辛酰基-sn-甘油-3-磷酸-（1′-肌醇））是具有较短酰基链的PI类似物。

Packaging

带塞子和压接盖的2 mL棕色血清瓶（850181P-100ug）
带塞子和压接盖的2 mL棕色血清瓶（850181P-500ug）

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available

历史批次信息供参考:

分析证书(COA)

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Endocytosis and the Endosomal Membrane System
Cell Biology, 377-392 (2017)
Marcelo E Guerin et al.
The Journal of biological chemistry, 282(28), 20705-20714 (2007-05-19)
Mycobacterial phosphatidylinositol mannosides (PIMs) and metabolically derived cell wall lipoglycans play important roles in host-pathogen interactions, but their biosynthetic pathways are poorly understood. Here we focus on Mycobacterium smegmatis PimA, an essential enzyme responsible for the initial mannosylation of phosphatidylinositol.
Inhibition of Phosphoinositide 3-Kinase and Acquired Long QT Syndrome
Cardiac Electrophysiology: From Cell to Bedside, 106-112 (2018)
Shuang Song et al.
Food chemistry, 240, 1171-1178 (2017-09-28)
Nuts, a class of fatty natural food, are associated with a series of health benefit. Lipid, which is the most abundant nutrient in nuts, could be one of the major contributors to many beneficial effects. In previous studies, only the
Zhen Chen et al.
Theriogenology, 144, 56-66 (2020-01-10)
A comparative lipidomic profiling analysis of dairy cattle oocytes with different developmental competences was performed using a combination of high performance liquid chromatography-high resolution tandem mass spectrometry and multivariate statistical analysis. Significant lipidomic changes were identified in degenerating oocytes. Total

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