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Merck
CN

850181P

Avanti

08:0 PI

Avanti Research™ - A Croda Brand

别名:

PI(8:0/8:0)

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关于此项目

经验公式（希尔记法）:
C25H50NO13P
CAS Number:
2260795-76-2
分子量:
603.64
UNSPSC代码:
51191904
NACRES:
NA.25

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Product Name

08:0 PI, 1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 100 μg (with stopper and crimp cap (850181P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850181P-500ug))

制造商/商品名称

Avanti Research™ - A Croda Brand 850181P

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]

InChI

1S/C25H47O13P.H3N/c1-3-5-7-9-11-13-18(26)35-15-17(37-19(27)14-12-10-8-6-4-2)16-36-39(33,34)38-25-23(31)21(29)20(28)22(30)24(25)32;/h17,20-25,28-32H,3-16H2,1-2H3,(H,33,34);1H3/t17-,20-,21-,22+,23-,24-,25-;/m1./s1

InChI key

BJQNDQRSJKQZAM-RGISUMIPSA-N

相关类别

一般描述

磷脂酰肌醇（PI）是一种甘油磷脂，具有带有环己醇部分的头基。08:1 PI（1,2-二辛酰基-sn-甘油-3-磷酸-（1′-肌醇））是具有较短酰基链的PI类似物。

应用

08:0 PI（1，2-二辛酰基-sn-甘油-3-磷酸-（1′-肌醇））可以用于：
  • 作为磷脂酰-肌醇甘露糖基转移酶（PimA）的底物来比较非底物磷脂对活性的效应
  • 在酶促测定中替代分枝杆菌膜以测量PimA活性
  • 作为离子阱飞行时间（IT-TOF）系统中的磷脂（PL）标准品，以研究独特PL的断裂原理，也用作坚果样品中PL定量分析的非内源PL标准品

生化/生理作用

磷脂酰肌醇（PI）充当磷酸肌醇（一类信号脂质）的前体。
肌醇磷脂物质是膜结合的信号分子，它参与细胞生理学的几乎所有方面，包括细胞生长、代谢、增殖和存活。

包装

带塞子和压接盖的2 mL棕色血清瓶（850181P-100ug）
带塞子和压接盖的2 mL棕色血清瓶（850181P-500ug）

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

闪点(°F)

No data available

闪点(°C)

No data available

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Inhibition of Phosphoinositide 3-Kinase and Acquired Long QT Syndrome
Cardiac Electrophysiology: From Cell to Bedside, 106-112 (2018)
Marcelo E Guerin et al.
The Journal of biological chemistry, 282(28), 20705-20714 (2007-05-19)
Mycobacterial phosphatidylinositol mannosides (PIMs) and metabolically derived cell wall lipoglycans play important roles in host-pathogen interactions, but their biosynthetic pathways are poorly understood. Here we focus on Mycobacterium smegmatis PimA, an essential enzyme responsible for the initial mannosylation of phosphatidylinositol.
Endocytosis and the Endosomal Membrane System
Cell Biology, 377-392 (2017)
Shuang Song et al.
Food chemistry, 240, 1171-1178 (2017-09-28)
Nuts, a class of fatty natural food, are associated with a series of health benefit. Lipid, which is the most abundant nutrient in nuts, could be one of the major contributors to many beneficial effects. In previous studies, only the
Zhen Chen et al.
Theriogenology, 144, 56-66 (2020-01-10)
A comparative lipidomic profiling analysis of dairy cattle oocytes with different developmental competences was performed using a combination of high performance liquid chromatography-high resolution tandem mass spectrometry and multivariate statistical analysis. Significant lipidomic changes were identified in degenerating oocytes. Total

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