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经验公式(希尔记法):
C15H18N8O5
化学文摘社编号:
分子量:
390.35
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
Regadenoson, 2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (850200P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850200P
application(s)
lipidomics
metabolomics
shipped in
dry ice
storage temp.
−20°C
SMILES string
[n]4(ncc(c4)C(=O)NC)c1nc2[n](cnc2c(n1)N)[C@@H]3O[C@@H]([C@H]([C@H]3O)O)CO
InChI
1S/C15H18N8O5/c1-17-13(27)6-2-19-23(3-6)15-20-11(16)8-12(21-15)22(5-18-8)14-10(26)9(25)7(4-24)28-14/h2-3,5,7,9-10,14,24-26H,4H2,1H3,(H,17,27)(H2,16,20,21)/t7-,9-,10-,14-/m1/s1
InChI key
LZPZPHGJDAGEJZ-AKAIJSEGSA-N
General description
Regadenoson is an adenosine analog.
Biochem/physiol Actions
Regadenoson (Lexiscan) is an A2A adenosine receptor agonist used as a coronary vasodilator in pharmacologic stress testing. Recently, it has been demonstrated that regadenoson can temporarily disrupt the integrity of the blood-brain barrier (BBB) by inhibiting P-glycoprotein function.
Regadenoson can be used in patients with obstructive lung disease and renal impairment for myocardial perfusion imaging (MPI).
Packaging
5 mL Amber Glass Screw Cap Vial (850200P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids