850334P
Avanti
MAPCHO™-10
Avanti Research™ - A Croda Brand
别名:
n-decylphosphocholine
产品名称
MAPCHO™-10, Avanti Research™ - A Croda Brand 850334P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 g (850334P-1g)
制造商/商品名称
Avanti Research™ - A Croda Brand 850334P
运输
dry ice
储存温度
−20°C
SMILES字符串
[P](=O)([O-])(OCC[N+](C)(C)C)OCCCCCCCCCC
InChI
1S/C15H34NO4P/c1-5-6-7-8-9-10-11-12-14-19-21(17,18)20-15-13-16(2,3)4/h5-15H2,1-4H3
InChI key
VVVDGSCGBGBGFN-UHFFFAOYSA-N
一般描述
MAPCHO™-10/n-decylphosphocholine (DPC) is a short-chain lipid like, zwitterionic detergent.
N-decylphosphocholine is a structural analog of decanoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid maybe used as a detergent for membrane protein solubilization and purification.
生化/生理作用
Dodecylphosphocholine (DPC) is mainly used to isolate and purify membrane proteins and it also acts as a membrane-mimetic micellar environment for liquid-state nuclear magnetic resonance (NMR) studies of membrane proteins.
包装
30 mL Amber Wide Mouth Bottle with Screw Cap (850334P-1g)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Magnetically oriented dodecylphosphocholine bicelles for solid-state NMR structure analysis
Nolandt OV, et al.
Biochimica et Biophysica Acta, 1818(5), 1142-1147 (2012)
Magnetically oriented dodecylphosphocholine bicelles for solid-state NMR structure analysis
Nolandt OV, et al.
Biochimica et Biophysica Acta (2012)
D Z Liu et al.
Journal of pharmaceutical sciences, 88(11), 1161-1168 (1999-11-17)
The intestinal epithelium is a significant barrier for oral absorption of hydrophilic drugs because they cannot easily traverse the lipid bilayer of the cell membrane and their passage through the intercellular space (paracellular transport) is restricted by the tight junctions.
Sheeja V Vasudevan et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(15), 6847-6851 (2010-03-31)
Repair of damage to the central nervous system (CNS) is inhibited by the presence of myelin proteins that prevent axonal regrowth. Consequently, growth inhibitors and their common receptor have been identified as targets in the treatment of injury to the
Reto Horst et al.
The journal of physical chemistry. B, 116(23), 6775-6780 (2012-02-18)
Aqueous solutions of the detergent Fos-10 (n-decylphosphocholine) without and with addition of the integral membrane protein (IMP) OmpX (outer membrane protein X) have been characterized using pulsed field gradient-stimulated echo (PFG-STE) NMR experiments for measurements of translational diffusion coefficients. Effective
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