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Merck
CN

850402C

Avanti

4ME 16:0 PE

Avanti Research - A Croda Brand

别名:

1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphoethanolamine; PE(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))

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关于此项目

经验公式(希尔记法):
C45H90NO8P
化学文摘社编号:
分子量:
804.17
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

4ME 16:0 PE, 1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine, chloroform

InChI

1S/C45H90NO8P/c1-35(2)17-11-19-37(5)21-13-23-39(7)25-15-27-41(9)31-44(47)51-33-43(34-53-55(49,50)52-30-29-46)54-45(48)32-42(10)28-16-26-40(8)24-14-22-38(6)20-12-18-36(3)4/h35-43H,11-34,46H2,1-10H3,(H,49,50)/t37?,38?,39?,40?,41?,42?,43-/m1/s1

InChI key

XLPHMKQBBCKEFO-DHYROEPTSA-N

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850402C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850402C

concentration

10 mg/mL (850402C-25mg)

lipid type

omega FAs

shipped in

dry ice

storage temp.

−20°C

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Application

4ME 16:0 PE is suitable for use in the preparation of Vaxfectin, a plasmid DNA vaccine. It may also be used in the oriented circular dichroism (OCD) experiment for the measurement of peptide orientation in lipid bilayers.

Packaging

5 mL Clear Glass Sealed Ampule (850402C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

危险化学品
易制毒化学品(2类)
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores
Hermanson G, et al.
Proceedings of the National Academy of Sciences of the USA, 101(37), 13601-13606 (2004)
Multiple states of beta-sheet peptide protegrin in lipid bilayers
Heller WT, et al.
Biochemistry, 37(49), 17331-17338 (1998)
Many-body effect of antimicrobial peptides: on the correlation between lipid?s spontaneous curvature and pore formation
Lee MT, et al.
Biophysical Journal, 89(6), 4006-4016 (2005)
Jianjun Pan et al.
The journal of physical chemistry. B, 116(51), 14829-14838 (2012-12-04)
Cholesterol and ether lipids are ubiquitous in mammalian cell membranes, and their interactions are crucial in ether lipid mediated cholesterol trafficking. We report on cholesterol's molecular interactions with ether lipids as determined using a combination of small-angle neutron and X-ray

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