产品名称
18:1-18:0 PC, 1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine, powder
form
powder
assay
>99% (TLC)
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O
InChI
1S/C44H86NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20,22,42H,6-19,21,23-41H2,1-5H3/b22-20-/t42-/m1/s1
InChI key
NMJCSTNQFYPVOR-VHONOUADSA-N
packaging
pkg of 1 × 25 mg (850476P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850476P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
Application
18:1-18:0 PC (1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine) may be used:
- as a lipid standard in ultra-performance liquid chromatography (UPLC) analyses
- in bilayer membranes to study the bilayer phase transitions
- in liposome as substrate to study the transacylase activities of different lysosomal phospholipase A2 (LPLA2) variants
Biochem/physiol Actions
Phosphatidylcholine (PC) intake through diet can enhance the learning and memory ability in rats.
General description
18:1-18:0 PC (1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine) is an asymmetric phospholipid.
Packaging
5 mL Clear Glass Sealed Ampule (850476P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Kaori Tada et al.
Biochimica et biophysica acta, 1788(5), 1056-1063 (2009-02-24)
The bilayer phase transitions of six kinds of mixed-chain phosphatidylcholines (PCs) with an unsaturated acyl chain in the sn-1 or sn-2 position, 1-oleoyl-2-stearoyl- (OSPC), 1-stearoyl-2-oleoyl- (SOPC), 1-oleoyl-2-palmitoyl- (OPPC), 1-palmitoyl-2-oleoyl- (POPC), 1-oleoyl-2-myristoyl- (OMPC) and 1-myristoyl-2-oleoyl-sn-glycero-3-phosphocholine (MOPC), were observed by means of
Katharina Wozny et al.
Analytical and bioanalytical chemistry, 411(4), 915-924 (2018-12-24)
Diacyl glycerophospholipids (GPs) belong to the most abundant lipid species in living organisms and consist of a glycerol backbone with fatty acyl groups in sn-1 and sn-2 and a polar head group in the sn-3 position. Regioisomeric mixed diacyl GPs
Vania Hinkovska-Galcheva et al.
Journal of lipid research, 59(7), 1205-1218 (2018-05-05)
Lysosomal phospholipase A2 (LPLA2) is characterized by broad substrate recognition, peak activity at acidic pH, and the transacylation of lipophilic alcohols, especially N-acetyl-sphingosine. Prior structural analysis of LPLA2 revealed the presence of an atypical acidic residue, Asp13, in the otherwise
Miao-Miao Zhou et al.
Lipids in health and disease, 15(1), 135-135 (2016-08-26)
Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well.
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features
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