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经验公式（希尔记法）:
C24H35NO
化学文摘社编号:
分子量:
353.54
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
Laurdan, Avanti Research™ - A Croda Brand
InChI key
JHDGGIDITFLRJY-UHFFFAOYSA-N
SMILES string
N(C)(C)c1cc2c(cc(cc2)C(=O)CCCCCCCCCCC)cc1
assay
99% (TLC)
form
powder
packaging
package of 1 × 100 μg
package of 1 × 500 μg
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
1-(6-(dimethylamino)naphthalen-2-yl) dodecan-1-one or Laurdan exhibits spectral sensitivity to phospholipid phase state. It also exhibits fluorescence property. Laurdan is implicated in bilayer property studies of natural and artificial membranes due to its sensitivity to solvent relaxation effect.
General description
1-(6-(dimethylamino)naphthalen-2-yl) dodecan-1-one or Laurdan is a derivative of naphthalene and is a fluorescent membrane probe. It is present at the hydrophilic-hydrophobic interface of the lipid bilayer, wherein the lauric acid tail is attached attached in the phospholipid acyl chain area.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (850582p-100UG) 2 mL Amber Serum Vial with Stopper and Crimp Cap (850582p-500UG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Two-photon fluorescence microscopy of laurdan generalized polarization domains in model and natural membranes
Parasassi T, et al.
Biophysical Journal, 72(6), 2413-2429 (1997)
Use of laurdan fluorescence intensity and polarization to distinguish between changes in membrane fluidity and phospholipid order
Harris F M, et al.
Biochimica et Biophysica Acta - Biomembranes, 1565(1), 123-128 (2002)
Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence.
Parasassi T, et al.
Biophysical Journal, 60(1), 179-179 (1991)
Laurdan and Prodan as polarity-sensitive fluorescent membrane probes
Parasassi T, et al.
Journal of Fluorescence, 8(4), 365-373 (1998)
商品
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