Product Name
06:0 PE, 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 25 mg (850697P-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 850697P
脂质类型
cardiolipins
phospholipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O
InChI
1S/C17H34NO8P/c1-3-5-7-9-16(19)23-13-15(26-17(20)10-8-6-4-2)14-25-27(21,22)24-12-11-18/h15H,3-14,18H2,1-2H3,(H,21,22)/t15-/m1/s1
InChI key
PELYUHWUVHDSSU-OAHLLOKOSA-N
一般描述
06:0 Phosphatidylethanolamine (PE) is a water-soluble short-chain glycero-phospholipid. It is primarily found in the inner leaflet of the plasma membrane.
Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15–25% of the total lipid in the cells of mammals.
应用
06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
- as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity assay
- as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
- as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants
06:0 Phosphatidylethanolamine (PE) has been used as a ligand in the co-crystallization of broadly neutralizing anti-HIV antibody 4E10. It has also been used as one of the phospholipids (PLs) standards for the analysis of bovine milk PL classes by normal-phase high-performance liquid chromatography (NP-HPLC).
生化/生理作用
06:0 Phosphatidylethanolamine (PE) plays an important role in various cellular processes such as autophagy, cell division and protein folding. In addition it also acts as a precursor for the synthesis of several protein modifications and as an intermediate in the synthesis of other glycerophospholipids.
Phosphoethanolamine (PE) serves as a precursor in membrane phospholipid biosynthesis. Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells.
包装
5 mL Clear Glass Sealed Ampule (850697P-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Liquid chromatographic analysis of milk phospholipids with on-line pre-concentration
Fagan P, et al.
Journal of Chromatography A, 1054(1-2), 241-249 (2004)
Crystallographic identification of lipid as an integral component of the epitope of HIV broadly neutralizing antibody 4E10
Irimia A, et al.
Immunity, 44(1), 21-31 (2016)
Peter Fagan et al.
Journal of chromatography. A, 1054(1-2), 241-249 (2004-11-24)
Two methods have been developed for the analysis of bovine milk phospholipid (PL) classes by NP-HPLC with evaporative light scattering detection. In the first method, a PVA-Sil guard column was used for the rapid determination of the major milk PL
S F Martin et al.
Biochemistry, 39(12), 3410-3415 (2000-03-22)
The phosphatidylcholine-preferring phospholipase C from Bacillus cereus (PLC(Bc)) is a 28.5 kDa enzyme with three zinc ions in its active site. The roles that a number of amino acid residues play as zinc ligands and in binding and catalysis have
Shingo Mineta et al.
Journal of bioscience and bioengineering, 119(2), 123-130 (2014-08-20)
Streptomyces sanglieri extracellularly produces a glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP). The gene encoding the enzyme was found to consist of a 2124-bp ORF, which codes for an N-terminal 48 residue signal peptide required for secretion and a 660 amino acid mature protein
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