产品名称
16:1 PE, 1,2-dipalmitoleoyl-sn-glycero-3-phosphoethanolamine, powder
InChI
1S/C37H70NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(39)43-33-35(34-45-47(41,42)44-32-31-38)46-37(40)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h13-16,35H,3-12,17-34,38H2,1-2H3,(H,41,42)/b15-13-,16-14-/t35-/m1/s1
InChI key
PGPMCWZMPPZJML-NAFNZUQFSA-N
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCC)=O)COC(CCCCCCC/C=C\CCCCCC)=O
assay
>99% (TLC)
form
powder
packaging
pkg of 2 × 100 mg (850706P-200mg), pkg of 1 × 25 mg (850706P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850706P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphatidylethanolamine is an aminophospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in biological membranes. Phosphatidylethanolamine is found in nervous tissue.
Application
16:1 PE has been used to assess the linearity of response of lipid classes. It has also been used as an internal standard for the determination of plasmenyl-PC and plasmenyl-PE of human heart mitochondria using a Bligh -Dyer extraction method.
Biochem/physiol Actions
Phosphatidylethanolamine forms pure lipid structures. It maintains membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a critical role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.
Packaging
5 mL Clear Glass Sealed Ampule (850706P-200mg)
5 mL Clear Glass Sealed Ampule (850706P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
The Membranes of Cells (2016)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
Cytochrome c is an oxidative stress-activated plasmalogenase that cleaves plasmenylcholine and plasmenylethanolamine at the sn-1 vinyl ether linkage
Jenkins CM, et al.
The Journal of Biological Chemistry, 293(22), 8693-8709 (2018)
High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors
Huynh K, et al.
Cell Chemical Biology, 26(1), 71-84 (2019)
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5, 16787-16787 (2015)
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