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850755C

Avanti

18:2 PE

Name: 18:2 PE
Brand: AVANTI

Avanti Research^™ - A Croda Brand

别名:

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine; PE(18:2(9Z,12Z)/18:2(9Z,12Z))

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关于此项目

经验公式（希尔记法）:

C₄₁H₇₄NO₈P

化学文摘社编号:

20707-71-5

分子量:

740.00

UNSPSC Code:

51191904

NACRES:

NA.25

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属性

产品名称

18:2 PE, 1,2-dilinoleoyl-sn-glycero-3-phosphoethanolamine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850755C-25mg), pkg of 2 × 4 mL (850755C-200mg)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 850755C

concentration

10 mg/mL (850755C-25mg), 25 mg/mL (850755C-200mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O

InChI

1S/C41H74NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h11-14,17-20,39H,3-10,15-16,21-38,42H2,1-2H3,(H,45,46)/b13-11-,14-12-,19-17-,20-18-/t39-/m1/s1

InChI key

SSCDRSKJTAQNNB-DWEQTYCFSA-N

说明

General description

Phosphatidylethanolamine (PE) is the second most plenteous glycerophospholipid in eukaryotic cells. It is a non-bilayer forming phospholipid, which is found majorly in the mitochondria. It consists of a small polar head group with fatty acid chains.

Application

18:2 PE has been used for the preparation of liposomes.

Biochem/physiol Actions

Phosphatidylethanolamine (PE) functions as to provide rigidity to the cell membranes via hexagonal phase structures which promote tight packing of the membrane bilayer formed by phosphatidylcholine. It is also involved in the conversion of prions from the non-toxic to toxic conformation. PE also initiates the autophagosome formation by attaching covalently to the autophagy Atg8 protein.

Packaging

5 mL Clear Glass Sealed Ampule (850755C-200mg)

5 mL Clear Glass Sealed Ampule (850755C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H302,H315,H319,H331,H336,H351,H361d,H372

pcodes

P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c