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Merck
CN

852758C

Avanti

C18(Plasm)-18:1 PE

Avanti Research™ - A Croda Brand

别名:

1-O-1′-(Z)-octadecenyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; GPEtn(18:0p/18:1(9Z)); 110645

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关于此项目

经验公式（希尔记法）:
C41H80NO7P
化学文摘社编号:
144371-68-6
分子量:
730.05
UNSPSC Code:
51191904
NACRES:
NA.25

主要文件

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产品名称

C18(Plasm)-18:1 PE, Avanti Research™ - A Croda Brand

InChI key

XVYPOHCSLJZFED-QZEVRULJSA-N

SMILES string

[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O

description

1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 5 mL (852758C-10mg)
pkg of 1 × 5 mL (852758C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

1 mg/mL (852758C-5mg)
2 mg/mL (852758C-10mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

Application

C18(Plasm)-18:1 PE has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS).

Biochem/physiol Actions

Phosphatidylethanolamine forms pure lipid structures, which regulate membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a major role in autophagy, cell division and protein folding. It functions as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine acts as an intermediate for the synthesis of glycerophospholipid classes.

General description

Phosphatidylethanolamine is an aminophospholipid. It is present in eukaryotic and prokaryotic cells. Phosphatidylethanolamine is one of the most abundant glycerophospholipids in the biological membranes. It is found in nervous tissue.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852758C-10mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852758C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

危险化学品
易制毒化学品（2类）
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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An Introduction to Biological Membranes: Composition, Structure and Function (2016)
The Membranes of Cells (2016)
Nathan R Deleault et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1938-E1946 (2012-06-20)
Prions containing misfolded prion protein (PrP(Sc)) can be formed with cofactor molecules using the technique of serial protein misfolding cyclic amplification. However, it remains unknown whether cofactors materially participate in maintaining prion conformation and infectious properties. Here we show that
Geoffrey P Noble et al.
Biochemistry, 54(5), 1180-1187 (2015-01-15)
Misfolding of the prion protein (PrP) plays a central role in the pathogenesis of infectious, sporadic, and inherited prion diseases. Here we use a chemically defined prion propagation system to study misfolding of the pathogenic PrP mutant D177N in vitro.
Ana West et al.
The journal of physical chemistry. B, 124(5), 828-839 (2020-01-10)
Ethanolamine plasmalogen (EtnPLA) is a conical-shaped ether lipid and an essential component of neurological membranes. Low stability against oxidation limits its study in experiments. The concentration of EtnPLA in the bilayer varies depending on cell type and disease progression. Here
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