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Merck
CN

852758C

Avanti

C18(Plasm)-18:1 PE

Avanti Research™ - A Croda Brand

别名:

1-O-1′-(Z)-octadecenyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; GPEtn(18:0p/18:1(9Z)); 110645

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关于此项目

经验公式（希尔记法）:
C41H80NO7P
CAS Number:
144371-68-6
分子量:
730.05
UNSPSC代码:
51191904
NACRES:
NA.25

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描述

1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 5 mL (852758C-10mg)
pkg of 1 × 5 mL (852758C-5mg)

制造商/商品名称

Avanti Research™ - A Croda Brand

浓度

1 mg/mL (852758C-5mg)
2 mg/mL (852758C-10mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O

InChI key

XVYPOHCSLJZFED-QZEVRULJSA-N

相关类别

一般描述

Phosphatidylethanolamine is an aminophospholipid. It is present in eukaryotic and prokaryotic cells. Phosphatidylethanolamine is one of the most abundant glycerophospholipids in the biological membranes. It is found in nervous tissue.

应用

C18(Plasm)-18:1 PE has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS).

生化/生理作用

Phosphatidylethanolamine forms pure lipid structures, which regulate membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a major role in autophagy, cell division and protein folding. It functions as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine acts as an intermediate for the synthesis of glycerophospholipid classes.

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852758C-10mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852758C-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Liver,Kidney, Respiratory system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品（2类）
危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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An Introduction to Biological Membranes: Composition, Structure and Function (2016)
The Membranes of Cells (2016)
Geoffrey P Noble et al.
Biochemistry, 54(5), 1180-1187 (2015-01-15)
Misfolding of the prion protein (PrP) plays a central role in the pathogenesis of infectious, sporadic, and inherited prion diseases. Here we use a chemically defined prion propagation system to study misfolding of the pathogenic PrP mutant D177N in vitro.
Nathan R Deleault et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1938-E1946 (2012-06-20)
Prions containing misfolded prion protein (PrP(Sc)) can be formed with cofactor molecules using the technique of serial protein misfolding cyclic amplification. However, it remains unknown whether cofactors materially participate in maintaining prion conformation and infectious properties. Here we show that
Fozia Saleem et al.
Prion, 8(2) (2014-05-14)
The conformational conversion of the cellular prion protein (PrP(C)) to the β-rich infectious isoform PrP(Sc) is considered a critical and central feature in prion pathology. Although PrP(Sc) is the critical component of the infectious agent, as proposed in the "protein-only"
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