产品名称
C18（血浆）-18:1 PE, 1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, powder
InChI
1S/C41H80NO7P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-36-46-38-40(39-48-50(44,45)47-37-35-42)49-41(43)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h18,20,33,36,40H,3-17,19,21-32,34-35,37-39,42H2,1-2H3,(H,44,45)/b20-18-,36-33-/t40-/m1/s1
InChI key
XVYPOHCSLJZFED-QZEVRULJSA-N
SMILES string
[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (852758P-10mg)
pkg of 1 × 5 mg (852758P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 852758P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
Application
C18（血浆）-18:1 PE已用于脂质纯化和脂肪酸提取。它也被用于脂多糖（LPS）介导的富含β的朊病毒蛋白PrPβ转化。
Biochem/physiol Actions
磷脂酰乙醇胺形成纯脂质结构。它保持真核细胞膜的流动性。磷脂酰乙醇胺在自噬、细胞分裂和蛋白质折叠中起重要作用。它是合成各种蛋白质修饰的前体。磷脂酰乙醇胺是合成甘油磷脂类的中间体。
General description
磷脂酰乙醇胺是一种氨基磷脂，存在于真核和原核细胞中。它是生物膜中最丰富的甘油磷脂之一。磷脂酰乙醇胺存在于神经组织中。
Packaging
5 mL棕色玻璃密封安瓿（852758P-10mg）
5 mL棕色玻璃螺旋盖小瓶（852758P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Lipopolysaccharide induced conversion of recombinant prion protein
Saleem F, et al.
Prion, 8(2), 221-232 (2014)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
The Membranes of Cells (2016)
Nathan R Deleault et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1938-E1946 (2012-06-20)
Prions containing misfolded prion protein (PrP(Sc)) can be formed with cofactor molecules using the technique of serial protein misfolding cyclic amplification. However, it remains unknown whether cofactors materially participate in maintaining prion conformation and infectious properties. Here we show that
Detection of unusual very-long-chain fatty acid and ether lipid derivatives in the fibroblasts and plasma of patients with peroxisomal diseases using liquid chromatography-mass spectrometry
Takashima S, et al.
Molecular Genetics and Metabolism, 120(3), 255-268 (2017)
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