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Merck
CN

852804C

Avanti

C18(Plasm)-20:4 PE

Avanti Research™ - A Croda Brand

别名:

1-O-1′-(Z)-octadecenyl-2--(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine; GPEtn(18:0p/20:4(5Z,8Z,11Z,14Z))

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关于此项目

经验公式（希尔记法）:
C43H78NO7P
化学文摘社编号:
144371-69-7
分子量:
752.06
UNSPSC Code:
51191904
NACRES:
NA.25

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产品名称

C18(Plasm)-20:4 PE, 1-(1Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphoethanolamine, chloroform

InChI

1S/C43H78NO7P/c1-3-5-7-9-11-13-15-17-19-21-22-24-26-28-30-32-34-36-43(45)51-42(41-50-52(46,47)49-39-37-44)40-48-38-35-33-31-29-27-25-23-20-18-16-14-12-10-8-6-4-2/h11,13,17,19,22,24,28,30,35,38,42H,3-10,12,14-16,18,20-21,23,25-27,29,31-34,36-37,39-41,44H2,

InChI key

URPXXNCTXCOATD-FXMFQVEGSA-N

SMILES string

[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 5 mL (852804C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 852804C

concentration

1 mg/mL (852804C-5mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

C18(Plasm)-20:4 PE has been used in the preparation of 2-arachidonic acid-lysophosphatidylethanolamine (2-AA-LPE). It has also been used in the synthesis of biotinylated analyte standard for reverse phase-high performance liquid chromatography (HPLC)-electrospray ionization-mass spectroscopy.

Biochem/physiol Actions

Plasmalogens are phospholipids, essential for cell function and signaling. Plasmalogens influences membrane structure and molecular dynamics, contributes to the functioning of integral membrane proteins. It plays an important role in the release of membrane fatty acid for signaling upon cell stimulation.

General description

C18(Plasm)-20:4 PE are plasmenylethanolamines that contains arachidonic acid. Plasmalogens, in general, contain a vinyl-ether linkage at the sn-1 position and at sn-2 position it is highly enriched with polyunsaturated fattyacid, specifically, arachidonic acid (AA).

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (852804C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

易制毒化学品（2类）
危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Identification and quantification of aminophospholipid molecular species on the surface of apoptotic and activated cells
Thomas CP, et al.
Nature Protocols, 9(1), 51-51 (2014)
Cytochrome c is an oxidative stress-activated plasmalogenase that cleaves plasmenylcholine and plasmenylethanolamine at the sn-1 vinyl ether linkage
Jenkins CM, et al.
The Journal of Biological Chemistry, 293(22), 8693-8709 (2018)

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