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Merck
CN

855575P

Avanti

14:0 Lyso PC

Avanti Research™ - A Croda Brand

别名:

1-十七烷酰基-sn-甘油-3-磷酸胆碱; PC(14:0/0:0)

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关于此项目

经验公式（希尔记法）:
C22H46NO7P
化学文摘社编号:
20559-16-4
分子量:
467.58
MDL number:
MFCD00036902
UNSPSC Code:
51191904
NACRES:
NA.25

主要文件

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产品名称

14:0 Lyso PC, 1-myristoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCC)=O

InChI

1S/C22H46NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-22(25)28-19-21(24)20-30-31(26,27)29-18-17-23(2,3)4/h21,24H,5-20H2,1-4H3/t21-/m1/s1

InChI key

VXUOFDJKYGDUJI-OAQYLSRUSA-N

assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 1 × 1 g (855575P-1g), pkg of 1 × 200 mg (855575P-200mg), pkg of 1 × 25 mg (855575P-25mg), pkg of 1 × 500 mg (855575P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 855575P

shipped in

dry ice

storage temp.

−20°C

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相关类别

Application

14:0 Lyso PC可以：
  • 用作洗涤剂胶束的成分，通过圆二色谱法（CD）分析纯化的双精氨酸转运（Tat）膜蛋白（TatCd）的二级结构
  • 用于合成三种单氟二豆蔻酰磷脂酰胆碱（F-DMPC′），例如2F-DMPC、12F-DMPC和14F-DMPC
  • 用作干脂质膜的成分，用于合成钯（Pd）-焦脂质诊疗纳米颗粒（PdPL-NP）和锰-焦脂质表面增强拉曼散射（SERS）NP（MnPL-NP）

14:0 Lyso PC被用于研究其在大鼠嗜铬细胞瘤PC12细胞中神经生长因子（NGF）诱导的丝裂原活化蛋白激酶（MAPK）和丝氨酸/苏氨酸蛋白激酶akt-1信号中的作用。

Packaging

20 mL透明玻璃螺旋盖样品瓶(855575P-1g)
20 mL透明玻璃螺旋盖样品瓶（855575P-500mg）
5 mL棕色玻璃螺旋盖样品瓶(855575P-200mg)
5 mL棕色玻璃螺旋盖样品瓶(855575P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nano-enabled SERS reporting photosensitizers
Farhadi A, et al.
Theranostics, 5(5), 469-469 (2015)
Structure analysis of the membrane protein TatCd from the Tat system of B. subtilis by circular dichroism
Nolandt OV, et al.
Biochimica et Biophysica Acta - Biomembranes, 1788(10), 2238-2244 (2009)
Lysophosphatidylcholine enhances NGF-induced MAPK and Akt signals through the extracellular domain of TrkA in PC12 cells
Itakura A, et al.
FEBS Open Bio, 3, 243-251 (2013)
Evaluation of the effect of fluorination on the property of monofluorinated dimyristoylphosphatidylcholines
Gagnon MC, et al.
Organic & Biomolecular Chemistry, 12(28), 5126-5135 (2014)
Baasanjav Uranbileg et al.
Scientific reports, 9(1), 16578-16578 (2019-11-14)
Cauda equina compression (CEC) is a major cause of neurogenic claudication and progresses to neuropathic pain (NP). A lipid mediator, lysophosphatidic acid (LPA), is known to induce NP via the LPA1 receptor. To know a possible mechanism of LPA production
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商品

Critical Micelle Concentrations (CMCs) - Avanti Research™ Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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