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关于此项目
经验公式（希尔记法）:
C19H38O7PNa
化学文摘社编号:
分子量:
432.46
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
产品名称
16：0 Lyso PA, Avanti Research™ - A Croda Brand
description
1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
assay
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
form
powder
packaging
pkg of 1 × 200 mg (857123P-200mg)
pkg of 1 × 25 mg (857123P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
Application
16:0 Lyso PA适合用作从卵巢癌患者血浆样品中提取脂质的内标。它也适合于制备用于合成脂质体的脂质溶液。
Biochem/physiol Actions
溶血磷脂酸（LPA）参与多种生物学功能。它是检测卵巢癌的潜在生物标志物。LPA可刺激血小板聚集、平滑肌收缩、趋化、细胞骨架重排、Ca2+动员、神经递质释放和细胞增殖。棕榈酰溶血磷脂酸会增加二磷酸腺苷（ADP）刺激的聚集。
General description
溶血磷脂酸（LPA）属于磷脂类，其甘油主链由磷酸基、脂肪链和羟基连接而成。它的磷酸基连接到sn-3位，脂肪链连接到sn-1或sn-2位，羟基连接到其余sn-1或sn-2位。
Packaging
5 mL棕色玻璃螺旋盖样品瓶（857123P-200mg）
5 mL棕色玻璃螺旋盖样品瓶（857123P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Maya Sawada et al.
Langmuir : the ACS journal of surfaces and colloids, 36(17), 4671-4681 (2020-04-10)
Amyloid fibrils are formed by denatured proteins when the supersaturation of denatured proteins is broken by agitation, such as ultrasonication, or by seeding, although the detailed mechanism of how solubility and supersaturation regulate amyloid formation remains unclear. To further understand
Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets
Benton AM, et al.
Blood, 60(3), 642-649 (1982)
The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling
Koprivanacz K, et al.
Cellular Signalling, 32(1-2), 66-75 (2017)
Quantitative determination of lysophosphatidic acid by LC/ESI/MS/MS employing a reversed phase HPLC column
Shan L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 864(1-2), 22-28 (2008)
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple
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