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Merck
CN

857135P

Avanti

18:1 BMP (S,S)

Avanti Research™ - A Croda Brand

别名:

lysobisphosphatidic acid; LBPA

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About This Item

经验公式（希尔记法）:
C42H82NO10P
CAS Number:
1246303-12-7
分子量:
792.07
UNSPSC代码:
51191904
NACRES:
NA.25

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Product Name

18:1 BMP (S,S), sn-(3-oleoyl-2-hydroxy)-glycerol-1-phospho-sn-1′-(3′-oleoyl-2′-hydroxy)-glycerol (ammonium salt), powder

方案

>99% (BMP (contains 30% positional isomers), TLC)

表单

powder

包装

pkg of 1 × 10 mg (857135P-10mg)
pkg of 1 × 5 mg (857135P-5mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 857135P

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@](COP(OC[C@@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

InChI

1S/C42H79O10P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-35-39(43)37-51-53(47,48)52-38-40(44)36-50-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,39-40,43-44H,3-16,21-38H2,1-2H3,(H,47,48);1H3/b19-17-,20-18-;/t39-,40-;/m0./s1

InChI key

YRFISMFFADMBIY-BXURRMQSSA-N

相关类别

一般描述

Bis(monoacylglycerol) phosphate (BMP) is a phospholipid containing two-phosphate linked fatty acid esterified glycerol molecule. It is present in late endosome, majorly in intraluminal vesicles (ILVs) and is hydrolyzed by BMP hydrolase. BMP accounts to 15% of total organelle lipids.

应用

18:1 BMP (S,S) may be used as an external standard for calibration in ultra performance liquid chromatography-mass spectrometry (UPLC-MS) and as an internal standard in liquid chromatography - tandem mass spectrometer (LC-MS) for quantification of lipids from tissues.It may also be used in liposome preparation for dengue virus fusion studies.

生化/生理作用

Bis(monoacylglycerol)phosphate (BMP) plays a key role in cargo sorting and protein and lipid trafficking. The levels of BMP is elevated in lysosomal storage disorders (LSD) including Wolman disease, Niemann Pick disease and neuronal ceroid lipofuscinoses. It is resistant to degradation by the enzyme, acid phospholipase.

包装

5 mL Clear Glass Sealed Ampule (857135P-10mg)
5 mL Clear Glass Sealed Ampule (857135P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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