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关于此项目
经验公式（希尔记法）:
C25H27N5O2
化学文摘社编号:
分子量:
429.51
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
VU0285655-1, N-{2-[4-oxo-1-phenyl-1,3,8-triazaspiro(4.5)decan-8-yl]ethyl}quinoline-3-carboxamide, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (857372P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 857372P
lipid type
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=C(C1=CN=C(C=CC=C2)C2=C1)NCCN(CC3)CCC43N(C5=CC=CC=C5)CNC4=O
InChI
1S/C25H27N5O2/c31-23(20-16-19-6-4-5-9-22(19)27-17-20)26-12-15-29-13-10-25(11-14-29)24(32)28-18-30(25)21-7-2-1-3-8-21/h1-9,16-17H,10-15,18H2,(H,26,31)(H,28,32)
InChI key
WJOCDBUFEUKYNI-UHFFFAOYSA-N
Application
VU0285655-1 has been used to study its role in membrane type 1 matrix metalloproteinase (MT1-MMP) surface trafficking and lung metastasis of mouse breast cancer cells. It has also been used as a phospholipase D-2 (PLD2) inhibitor to study its role in regulated exocytosis.
Biochem/physiol Actions
VU0285655-1 or N-2-[4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decan-8-yl]ethyl quinoline-3-carboxamide is a phospholipase D-2 (PLD2) inhibitor. It promotes autophagy in colorectal cancer cells.
Packaging
5 mL Amber Glass Screw Cap Vial (857372P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3