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Merck
CN

857461P

Avanti

16:1 aldehyde-d5

Avanti Research - A Croda Brand

别名:

110837

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经验公式(希尔记法):
C16H25OD5
化学文摘社编号:
分子量:
243.44
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
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产品名称

16:1 aldehyde-d5, (2E)-hexadecenal(d5), powder

InChI

1S/C16H30O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h14-16H,2-13H2,1H3/b15-14+/i1D3,2D2

InChI key

KLJFYXOVGVXZKT-AKCNZVNDSA-N

SMILES string

[2H]C([2H])([2H])C([2H])([2H])CCCCCCCCCCC/C=C/C([H])=O

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (857461P-1mg), pkg of 1 × 5 mg (857461P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 857461P

lipid type

sphingolipids
deuterated lipids

shipped in

dry ice

storage temp.

−20°C

General description

Fatty aldehydes are enzymatically converted to fatty alcohols and fatty acids. When assessing S1P lyase enzymatic activity, the estimation of fatty aldehyde stability during the reaction is required. The (2E)-hexadecenal(d5) (857461) is suitable as the internal standard for LC/MS/MS approaches to quantify the product of S1P degradation by S1P lyase, (2E)-hexadecenal; however, a natural (2E)-hexadecenal (857469) is needed to evaluate its stability during enzymatic reaction. The method describing the details of the use of both (2E)-hexadecenal(d5) and (2E)-hexadecenal for LC/MS/MS-based characterization of S1P lyase reaction is in preparation for publication by Berdyshev et al.Personal communication from Evgeny Berdyshev, Ph.D., Assistant Professor, University of Illinois at Chicago.

Application

16:1 aldehyde-d5 has been used as an internal standard in lipid extraction from lung tissue and liquid chromatography/with tandem mass spectrometry analysis (LC/MS/MS). It has also been used as a standard in lipid extraction from plasma, derivatization of 2E-hexadecenal for quantification in quadrupole/time-of-flight (QTOF) mass spectrometer connected with a rapid-resolution-liquid-chromatography (RRLC).

Biochem/physiol Actions

16:1 aldehyde is a predominant fatty aldehyde in phospholipid of bovine adipose tissue, Lactobacillus and few bacteria like Selenomonas ruminantium, when grown on glucose and even-numbered volatile fatty acids. It is one of the main aldehydes in plasmalogen of notched brittle star, Ophiura sarsi.

Packaging

5 mL Amber Glass Screw Cap Vial (857461P-1mg)
5 mL Amber Glass Screw Cap Vial (857461P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Novel methods for the quantification of (2E)-hexadecenal by liquid chromatography with detection by either ESI QTOF tandem mass spectrometry or fluorescence measurement
Luth A, et al.
Analytica Chimica Acta, 722(8), 70-79 (2012)
Marine Biogenic Lipids, Fats & Oils, 213-213 (1989)
Ether Lipids Chemistry and Biology, 335-335 (2012)
Cellular fatty acid and fatty aldehyde composition of rumen bacteria
Miyagawa E
The Journal of General and Applied Microbiology, 28(5), 389-408 (1982)
Lipid Metabolism in Ruminant Animals (2014)

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