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经验公式（希尔记法）:
C12H21NO3
化学文摘社编号:
分子量:
227.30
UNSPSC Code:
12352211
NACRES:
NA.25
MDL number:
Beilstein/REAXYS Number:
8148282
产品名称
N -辛酰- L -高丝氨酸内酯, (S)-N-(2-Oxotetrahydrofuran-3-yl)octanamide, powder
InChI key
JKEJEOJPJVRHMQ-JTQLQIEISA-N
SMILES string
O=C1OCC[C@@H]1NC(CCCCCCC)=O
InChI
1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (857521P-10MG)
pkg of 1 × 50 mg (857521P-50MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
bacterial lipids
shipped in
dry ice
storage temp.
−20°C
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Biochem/physiol Actions
群体感应信号产生
N-Octanoyl-L-homoserine lactone (C8-HSL) is produced by many gram-negative bacteria like Pseudomonas fluorescens, Ralstonia solanacearum, Vibrio fischeri, and Yersinia pseudotuberculosis. In Escherichia coli, C8-HSL is encoded by the gene Ytb1. Generally, these homoserine lactones (HSLs) are quorum sensing signaling molecules. HSLs play a key role in biofilm formation. They function as an autoinducer molecule and involved in cell to cell communication depending on cell density population.
General description
N-Octanoyl-L-homoserine lactone (C8-HSL) is a N-acyl homoserine lactone (N-acyl-HSL). It is highly nonpolar.
Packaging
5 mL Amber Glass Screw Cap Vial (857521P-10MG and 857521P-50MG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
A hierarchical quorum-sensing system in Yersinia pseudotuberculosis is involved in the regulation of motility and clumping.
Atkinson S, et al.
Molecular Microbiology, 33(6), 1267-1277 (1999)
Characterization of N-acylhomoserine lactones produced by bacteria isolated from industrial cooling water systems.
Okutsu N, et al.
Sensors, 16(1), 44-44 (2016)
P D Shaw et al.
Proceedings of the National Academy of Sciences of the United States of America, 94(12), 6036-6041 (1997-06-10)
Many Gram-negative bacteria regulate gene expression in response to their population size by sensing the level of acyl-homoserine lactone signal molecules which they produce and liberate to the environment. We have developed an assay for these signals that couples separation
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