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关于此项目
经验公式（希尔记法）:
C24H46O9PNa
化学文摘社编号:
分子量:
532.58
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
产品名称
18:1 Lyso PG, 1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform
assay
>99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)
form
liquid
packaging
pkg of 5 × 4 mL (858125C-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 858125C
concentration
25 mg/mL (858125C-500mg)
shipped in
dry ice
storage temp.
−20°C
Application
18:1 Lyso PG has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions.
Biochem/physiol Actions
Lyso phosphoglycerol (Lyso PG) and acyl-CoA acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) to synthesize phosphoglycerol. Lyso-phospholipids are nonbilayer-forming lipids. Accumulation of lysophospholipids in bacterial membranes disrupt the membrane integrity due to its detergent- like physical property.
General description
18:1 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are produced in γ-proteobacteria by lipoprotein acyltransferase activity. These lipids are found in minimal amount in normal bacterial membranes.
Packaging
5 mL Clear Glass Sealed Ampule (858125C-500mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Expression, purification and reconstitution of the C-terminal transmembrane domain of scavenger receptor BI into detergent micelles for NMR analysis
Chadwick A, et al.
Protein Expression and Purification, 107, 35-42 (2015)
Comprehensive untargeted lipidomic analysis using core-shell C30 particle column and high field orbitrap mass spectrometer
Narvaez-Rivas M and Zhang Q
Journal of Chromatography A, 1440, 123-134 (2016)
Hideo Shindou et al.
The Journal of biological chemistry, 284(1), 1-5 (2008-08-23)
Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.
Substrate selectivity of lysophospholipid transporter LplT involved in membrane phospholipid remodeling in Escherichia coli
Lin Y, et al.
The Journal of Biological Chemistry, 291(5), 2136-2149 (2016)
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate
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