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关于此项目
经验公式（希尔记法）:
C24H46O9PNa
化学文摘社编号:
分子量:
532.58
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
Lyso PG 18:1, 1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder
InChI
1S/C24H47O9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(28)31-19-23(27)21-33-34(29,30)32-20-22(26)18-25;/h9-10,22-23,25-27H,2-8,11-21H2,1H3,(H,29,30);/q;+1/p-1/b10-9-;/t22?,23-;/m1./s1
InChI key
STLDIXSFXILIFT-AXFOVFEGSA-M
SMILES string
[H][C@@](COP([O-])(OCC(O)CO)=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
assay
>99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)
form
powder
packaging
pkg of 1 × 1 g (858125P-1g)
pkg of 5 × 100 mg (858125P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 858125P
shipped in
dry ice
storage temp.
−20°C
Application
18:1 Lyso PG可用于：
- 制备脂质体
- 测定磷酸甘油（PG）和心磷脂（CL）对F0F1 ATPase c亚基（F0-c）转化的影响
- 作为酰基受体确定重组G0/G1开关基因2（G0S2）对酰基受体的底物特异性
Biochem/physiol Actions
溶血磷酸甘油（Lyso PG）是溶血磷脂酰甘油酰基转移酶1（LPGAT1）的底物，可用于合成磷酸甘油。溶血磷脂在细菌膜中的积累由于其类似洗涤剂的物理性质而干扰了膜的完整性。
General description
18:1溶血磷酸甘油是一种溶血磷脂洗涤剂。溶血磷脂是在γ-变形菌体内合成。它们是非双层形成脂质，，以非常微量的量存在。
Packaging
5 mL透明玻璃密封安瓿（858125P-500mg）
60 mL棕色广口螺旋盖玻璃瓶（858125P-1g）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Membrane insertion of F0 c subunit of F0F1 ATPase depends on glycolipozyme MPIase and is stimulated by YidC
Nishikawa H, et al.
Biochemical and Biophysical Research Communications, 487(2), 477-482 (2017)
Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2)
Zhang X, et al.
Faseb Journal, 33(5), 6655-6666 (2019)
Lipid bilayer modules as determinants of K+ channel gating
Syeda R, et al.
Test, 289(7), 4233-4243 (2014)
Expression, purification and reconstitution of the C-terminal transmembrane domain of scavenger receptor BI into detergent micelles for NMR analysis
Chadwick A, et al.
Protein Expression and Purification, 107, 35-42 (2015)
Hideo Shindou et al.
The Journal of biological chemistry, 284(1), 1-5 (2008-08-23)
Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.
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