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关于此项目
经验公式（希尔记法）:
C23H44NaO9P
化学文摘社编号:
分子量:
518.55
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
产品名称
17:1 Lyso PG, 1-(10Z-heptadecenoyl)-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform
assay
>99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)
form
liquid
packaging
pkg of 1 × 1 mL (858127C-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 858127C
concentration
5 mg/mL (858127C-5mg)
shipped in
dry ice
storage temp.
−20°C
Application
17:1 Lyso PG has been used as a standard for lipid profiling of rat peritoneal surface layers in liquid chromatography-mass spectrometry (LC-MS) method .
Biochem/physiol Actions
Lyso phosphoglycerol (Lyso PG) and acyl-CoA facilitates the synthesis of phosphoglycerol using lysophosphatidylglycerol acyltransferase 1 (LPGAT1). Lysophospholipids exhibits detergent- like physical property.
General description
Lyso-phospholipids are non bilayer-forming lipids, which are produced in γ-proteobacteria. They are present in normal bacterial membranes.
Packaging
5 mL Clear Glass Sealed Ampule (858127C-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Lipid profiling of rat peritoneal surface layers by online normal-and reversed-phase 2D LC QToF-MS
Nie H, et al.
Journal of Lipid Research, 51(9), 2833-2844 (2010)
Hideo Shindou et al.
The Journal of biological chemistry, 284(1), 1-5 (2008-08-23)
Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.
Substrate selectivity of lysophospholipid transporter LplT involved in membrane phospholipid remodeling in Escherichia coli
Lin Y, et al.
The Journal of Biological Chemistry, 291(5), 2136-2149 (2016)
Jordon M Inloes et al.
Biochemistry, 57(39), 5759-5767 (2018-09-18)
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which is characterized by axonal neuropathy and gait impairments. DDHD1 has been shown to display PLA1-type phospholipase
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